In the framework of Berthelot’s theory of arithmetic D\documentclass[12pt]{minimal}
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\begin{document}$${\mathcal {D}}$$\end{document}-modules, we prove that Berthelot’s characteristic variety associated with a holonomic D\documentclass[12pt]{minimal}
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\begin{document}$${\mathcal {D}}$$\end{document}-modules endowed with a Frobenius structure has pure dimension. As an application, we get the lagrangianity of the characteristic variety of a log extendable overconvergent F-isocrystal.