A small molecule enhances RNA interference and promotes microRNA processing

被引：0
|
作者：
Ge Shan
Yujing Li
Junliang Zhang
Wendi Li
Keith E Szulwach
Ranhui Duan
Mohammad A Faghihi
Ahmad M Khalil
Lianghua Lu
Zain Paroo
Anthony W S Chan
Zhangjie Shi
Qinghua Liu
Claes Wahlestedt
Chuan He
Peng Jin
机构：
[1] Emory University School of Medicine,Department of Human Genetics
[2] The University of Chicago,Department of Chemistry
[3] The Scripps Research Institute,Department of Molecular and Integrative Neurosciences
[4] University of Texas Southwestern Medical Center,Department of Biochemistry
[5] The College of Chemistry,undefined
[6] Peking University,undefined
来源：
Nature Biotechnology | 2008年 / 26卷
关键词：
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中图分类号：
学科分类号：
摘要：
Little is known about the regulation of RNA interference (RNAi). Shan et al. constructed a reporter system to monitor RNAi activity and identified a small molecule that increases RNAi by facilitating the interaction between small RNAs and a protein involved in small RNA loading and processing.
引用
收藏
页码：933 / 940
页数：7
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