Insulin in combination with pioglitazone prevents advanced cachexia in 256-Walker tumor-bearing rats: effect is greater than treatment alone and is associated with improved insulin sensitivity

被引：0
|
作者：
Daniele Romani Miksza
Giuliana Regina Biazi
Isabele Gonçalves Frasson
Winny Beatriz de Souza Galia
Laura Socio Ferraz
Brenda Francisconi Diaz
Mirian Ayumi Kurauti
Carine Marmentini
Cecília Edna Mareze-Costa
Sidney Barnabé Peres
Priscila Cassolla
Gisele Lopes Bertolini
Roberto Barbosa Bazotte
Helenir Medri de Souza
机构：
[1] State University of Londrina,Department of Physiological Sciences
[2] State University of Maringá,Department of Physiological Sciences
[3] Campinas State University,Department of Structural and Functional Biology
[4] State University of Maringá,Department of Pharmacology and Therapeutics
来源：
Pharmacological Reports | 2023年 / 75卷
关键词：
Cancer; Weight loss; Hypoinsulinemia; Insulin resistance; Pharmacological treatment;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1571 / 1587
页数：16
相关论文
共 19 条
  • [11] Effects of metformin on insulin resistance and metabolic disorders in tumor-bearing rats with advanced cachexia
    Silva, Flaviane de Fatima
    Ortiz-Silva, Milene
    de Souza Galia, Winny Beatriz
    Cassolla, Priscila
    da Silva, Francemilson Goulart
    Rodrigues Graciano, Maria Fernanda
    Carpinelli, Angelo Rafael
    de Souza, Helenir Medri
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2018, 96 (05) : 498 - 505
  • [12] Fish oil supplementation in F1 generation associated with naproxen, clenbuterol, and insulin administration reduce tumor growth and cachexia in Walker 256 tumor-bearing rats
    Pinto, JA
    Folador, A
    Bonato, SJ
    Aikawa, J
    Yamazaki, RK
    Pizato, N
    Facin, M
    Grohs, H
    de Oliveira, HHP
    Naliwaiko, K
    Ferraz, AC
    Nishiyama, A
    Fernandez, R
    Curi, R
    Fernandes, LC
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2004, 15 (06): : 358 - 365
  • [13] Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats
    Moreira, Veridiana Mota
    da Silva Franco, Claudineia Conationi
    Prates, Kelly Valerio
    Gomes, Rodrigo Mello
    Praxedes de Moraes, Ana Maria
    Ribeiro, Tatiane Aparecida
    Martins, Isabela Peixoto
    Previate, Carina
    Pavanello, Audrei
    Ianoni Matiusso, Camila Cristina
    Almeida, Douglas Lopes
    Francisco, Flavio Andrade
    Malta, Ananda
    Tofolo, Laize Peron
    Silveira, Sandra da Silva
    Jacinto Saavedra, Lucas Paulo
    Machado, Katia
    Olivieri da Silva, Paulo Henrique
    Fabricio, Gabriel S.
    Palma-Rigo, Kesia
    de Souza, Helenir Medri
    Silva, Flaviane de Fatima
    Biazi, Giuliana Regina
    Pereira, Tais Susane
    Vieira, Elaine
    Miranda, Rosiane Aparecida
    de Oliveira, Julio Cezar
    da Costa Lima, Luiz Delmar
    Rinaldi, Wilson
    Ravanelli, Maria Ida
    de Freitas Mathias, Paulo Cezar
    FRONTIERS IN PHYSIOLOGY, 2018, 9
  • [14] Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats
    Rafael Deminice
    Paola Sanches Cella
    Camila S. Padilha
    Fernando H. Borges
    Lilian Eslaine Costa Mendes da Silva
    Patrícia L. Campos-Ferraz
    Alceu Afonso Jordao
    Jason Lorne Robinson
    Robert F. Bertolo
    Rubens Cecchini
    Flávia Alessandra Guarnier
    Amino Acids, 2016, 48 : 2015 - 2024
  • [15] Creatine supplementation prevents hyperhomocysteinemia, oxidative stress and cancer-induced cachexia progression in Walker-256 tumor-bearing rats
    Deminice, Rafael
    Cella, Paola Sanches
    Padilha, Camila S.
    Borges, Fernando H.
    Costa Mendes da Silva, Lilian Eslaine
    Campos-Ferraz, Patricia L.
    Jordao, Alceu Afonso
    Robinson, Jason Lorne
    Bertolo, Robert F.
    Cecchini, Rubens
    Guarnier, Flavia Alessandra
    AMINO ACIDS, 2016, 48 (08) : 2015 - 2024
  • [16] Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats
    de Brito Bello, Sergio Ricardo
    Naliwaiko, Katya
    Vicentini, Mariana Scudeller
    Rossetti, Francini Xavier
    Fernandes, Luiz Claudio
    de Messias-Reason, Iara Jose
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2019, 71 (01): : 111 - 117
  • [17] Supplementation with L-glutamine prevents tumor growth and cancer-induced cachexia as well as restores cell proliferation of intestinal mucosa of Walker-256 tumor-bearing rats
    Martins, Heber Amilcar
    Sehaber, Camila Caviquioli
    Hermes-Uliana, Catchia
    Mariani, Fernando Augusto
    Guarnier, Flavia Alessandra
    Vicentini, Geraldo Emilio
    Piovezana Bossolani, Gleison Daion
    Jussani, Laraine Almeida
    Lima, Mariana Machado
    Bazotte, Roberto Barbosa
    Zanoni, Jacqueline Nelisis
    AMINO ACIDS, 2016, 48 (12) : 2773 - 2784
  • [18] Supplementation with l-glutamine prevents tumor growth and cancer-induced cachexia as well as restores cell proliferation of intestinal mucosa of Walker-256 tumor-bearing rats
    Heber Amilcar Martins
    Camila Caviquioli Sehaber
    Catchia Hermes-Uliana
    Fernando Augusto Mariani
    Flavia Alessandra Guarnier
    Geraldo Emílio Vicentini
    Gleison Daion Piovezana Bossolani
    Laraine Almeida Jussani
    Mariana Machado Lima
    Roberto Barbosa Bazotte
    Jacqueline Nelisis Zanoni
    Amino Acids, 2016, 48 : 2773 - 2784
  • [19] β-hydroxy-β-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-κB expression
    Nunes, Everson Araujo
    Kuczera, Diogo
    Pereira Brito, Gleisson Alisson
    Bonatto, Sandro J. R.
    Yamazaki, Ricardo Key
    Tanhoffer, Ricardo Antonio
    Mund, Rogeria Campus
    Kryczyk, Marcelo
    Fernandes, Luiz Claudio
    NUTRITION RESEARCH, 2008, 28 (07) : 487 - 493
12