Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters

被引：0

作者：

J. Brunner

Th. Bronisch

M. Uhr

M. Ising

E. Binder

F. Holsboer

C. W. Turck

机构：

[1] Facharzt für Psychiatrie und Psychotherapie,

来源：

European Archives of Psychiatry and Clinical Neuroscience | 2005年 / 255卷

关键词：

major depressive disorder; suicide attempt; proteomic analysis; cerebrospinal fluid;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

This is the first report on proteomic analysis of the cerebrospinal fluid (CSF) in unmedicated suicide attempters and non-attempters with major depressive disorder.Two-dimensional (2D) gel electrophoresis revealed that suicide attempters differed from non-attempters in one protein with an approximate molecular weight of 33 kD and an isoelectric point of 5.2. Proteomic analysis of the CSF is a promising non hypothesis-driven screening method for the detection of new candidate genes in neurobiological suicide research.

引用

页码：438 / 440

页数：2

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[1] Proteomic analysis of the CSF in unmedicated patients with major depressive disorder reveals alterations in suicide attempters
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Turck, CW
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