Nondestructive, base-resolution sequencing of 5-hydroxymethylcytosine using a DNA deaminase

被引:0
|
作者
Emily K Schutsky
Jamie E DeNizio
Peng Hu
Monica Yun Liu
Christopher S Nabel
Emily B Fabyanic
Young Hwang
Frederic D Bushman
Hao Wu
Rahul M Kohli
机构
[1] University of Pennsylvania,Department of Medicine
[2] University of Pennsylvania,Department of Genetics
[3] University of Pennsylvania,Department of Microbiology
[4] Penn Epigenetics Institute,undefined
[5] University of Pennsylvania,undefined
来源
Nature Biotechnology | 2018年 / 36卷
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学科分类号
摘要
A bisulfite-free sequencing method yields high-confidence 5hmC profiles in low-input samples.
引用
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页码:1083 / 1090
页数:7
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