Design and Analysis Considerations for a Sequentially Randomized HIV Prevention Trial

被引：0

作者：

David Benkeser

Keith Horvath

Cathy J. Reback

Joshua Rusow

Michael Hudgens

机构：

[1] Friends Research Institute,

[2] Inc,undefined

来源：

Statistics in Biosciences | 2020年 / 12卷

关键词：

Randomized trial; SMART; HIV prevention; Targeted learning; MHealth;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The TechStep study is an ongoing randomized controlled trial in HIV-negative transgender youths and young adults, which will evaluate the efficacy of mobile health interventions for reducing risk behaviors. Several mobile interventions are available, which complicates the design. To evaluate different combinations of mHealth interventions, TechStep is utilizing a sequentially randomized design. In this work, we discuss the motivation for this design, propose robust methodology for the analysis of the trial, and evaluate the methodology via simulation.

引用

页码：446 / 467

页数：21

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