Influence of the Nature of Amino Acids on the Formation of Supramolecular Complexes with Calixarenemethylene-bis-Phosphonic Acid

The formation of supramolecular complexes of 3-methyl-sulfido-propoxycalix[4]arene-methylene-bis-phosphonic acid with seventeen amino acids in aqueous solutions has been studied and their stability coefficients have been determined by the method of high-performance liquid chromatography. The structures of the supramolecular complexes have been proposed by molecular modeling and the influence of structural factors (the stabilization of different conformations of the obtained complexes depending on amino acid nature: possibilities of the realization of hydrogen bonds and electrostatic interactions between different groups of the amino acids and calixarene) on the stability of the supramolecules has been shown.