Synthesis of 1,8–Naphthyridines and Their Application in the Development of Anionic Fluorogenic Chemosensors

被引：0

作者：

Celso R. Nicoleti

Diogo N. Garcia

Luiz E. da Silva

Iêda M. Begnini

Ricardo A. Rebelo

Antonio C. Joussef

Vanderlei G. Machado

机构：

[1] Universidade Regional de Blumenau,Departamento de Química

[2] FURB,Departamento de Química

[3] Universidade Federal de Santa Catarina,undefined

[4] UFSC,undefined

[5] Universidade Federal do Paraná,undefined

[6] UFPR,undefined

[7] Setor Litoral,undefined

来源：

Journal of Fluorescence | 2012年 / 22卷

关键词：

Displacement assays; Copper; Anion sensing; Cyanide; 1,8–naphthyridines; Fluorogenic chemosensors;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Two 1,8–naphthyridines were synthesized and found to be fluorescent in solution. These compounds were studied in the presence of Cu+ and Cu2+ ions and it was verified that the metal causes the quenching of their fluorescence emission, due to the formation of complexes between the naphthyridine and the metal. A displacement assay was carried out in a DMSO–water mixture with the addition of various anions to the solutions of the complexes, and it was observed that these systems have a high capacity to selectively detect cyanide.

引用

页码：1033 / 1046

页数：13

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