Control of a Community-Wide Outbreak of Hepatitis A by Mass Vaccination with Inactivated Hepatitis A Vaccine

被引：0

作者：

C. Zamir

S. Rishpon

D. Zamir

A. Leventhal

N. Rimon

E. Ben-Porath

机构：

[1] Jerusalem District Health Office,

[2] Ministry of Health,undefined

[3] 86 Jaffa Road,undefined

[4] Jerusalem 94341,undefined

[5] Israel e-mail: hdrzamir@matat.health.gov.il Tel.: +972-2-4314800 Fax: +972-2-5314861,undefined

[6] Haifa District Health Office,undefined

[7] Haifa,undefined

[8] Israel,undefined

[9] Department of Medicine D,undefined

[10] Barzilai Medical Center,undefined

[11] Ashkelon,undefined

[12] Israel,undefined

[13] Public Health Services,undefined

[14] Ministry of Health,undefined

[15] Jerusalem,undefined

[16] Israel,undefined

[17] Microbiology Laboratory,undefined

[18] Rambam Medical Center,undefined

[19] Haifa,undefined

[20] Israel,undefined

来源：

European Journal of Clinical Microbiology and Infectious Diseases | 2001年 / 20卷

关键词：

Hepatitis; Effective Intervention; Immune Globulin; Immunization Program; Mass Vaccination;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The epidemiology and control of hepatitis A virus was investigated during an outbreak of hepatitis A in a village in Israel. Postexposure administration of immune globulin to contacts was ineffective in controlling the outbreak. However, within 2 weeks of starting a mass immunization campaign with hepatitis A vaccine, the incidence of hepatitis A declined dramatically; the last case occurred 6 weeks after the immunization program began. The study demonstrated that while postexposure administration of immune globulin may diminish but not entirely arrest transmission of hepatitis A virus, active hepatitis A vaccination is a safe and effective intervention that can be used safely in hepatitis A virus antibody-positive children.

引用

页码：185 / 187

页数：2

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