Control of a Community-Wide Outbreak of Hepatitis A by Mass Vaccination with Inactivated Hepatitis A Vaccine

被引:0
|
作者
C. Zamir
S. Rishpon
D. Zamir
A. Leventhal
N. Rimon
E. Ben-Porath
机构
[1] Jerusalem District Health Office,
[2] Ministry of Health,undefined
[3] 86 Jaffa Road,undefined
[4] Jerusalem 94341,undefined
[5] Israel e-mail: hdrzamir@matat.health.gov.il Tel.: +972-2-4314800 Fax: +972-2-5314861,undefined
[6] Haifa District Health Office,undefined
[7] Haifa,undefined
[8] Israel,undefined
[9] Department of Medicine D,undefined
[10] Barzilai Medical Center,undefined
[11] Ashkelon,undefined
[12] Israel,undefined
[13] Public Health Services,undefined
[14] Ministry of Health,undefined
[15] Jerusalem,undefined
[16] Israel,undefined
[17] Microbiology Laboratory,undefined
[18] Rambam Medical Center,undefined
[19] Haifa,undefined
[20] Israel,undefined
关键词
Hepatitis; Effective Intervention; Immune Globulin; Immunization Program; Mass Vaccination;
D O I
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学科分类号
摘要
 The epidemiology and control of hepatitis A virus was investigated during an outbreak of hepatitis A in a village in Israel. Postexposure administration of immune globulin to contacts was ineffective in controlling the outbreak. However, within 2 weeks of starting a mass immunization campaign with hepatitis A vaccine, the incidence of hepatitis A declined dramatically; the last case occurred 6 weeks after the immunization program began. The study demonstrated that while postexposure administration of immune globulin may diminish but not entirely arrest transmission of hepatitis A virus, active hepatitis A vaccination is a safe and effective intervention that can be used safely in hepatitis A virus antibody-positive children.
引用
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页码:185 / 187
页数:2
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