A model for dynamics of primer extension by eukaryotic DNA primase

被引:0
|
作者
Ping Xie
机构
[1] Chinese Academy of Sciences,Key Laboratory of Soft Matter Physics and Beijing National Laboratory for Condensed Matter Physics, Institute of Physics
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关键词
DNA primase; Primer synthesis; Model;
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暂无
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学科分类号
摘要
A mathematical model is proposed for processive primer extension by eukaryotic DNA primase. The model uses available experimental data to predict rate constants for the dynamic behavior of primase activity as a function of NTP concentration. The model also predicts some data such as the binding affinities of the primase for the DNA template and for the RNA primer.
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页码:1157 / 1165
页数:8
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