Neuroprotection for ischemic stroke using hypothermia

被引:0
|
作者
Angelos-Aristeidis Konstas
Jae H. Choi
John Pile-Spellman
机构
[1] Columbia University,Department of Radiology
来源
Neurocritical Care | 2006年 / 4卷
关键词
Hypothermia; neuroprotection; stroke; animal models; clinical trials;
D O I
暂无
中图分类号
学科分类号
摘要
The development of animal models of acute stroke has allowed the evaluation of mild and moderate hypothermia as a therapeutic modality in this clinical setting. Studies have demonstrated that animals subjected to hypothermia up to 3 hours after the primary central nervous system insult have reduced mortality and neuronal injury, and improved neurological outcome. These results warranted the evaluation of hypothermia in clinical trials.
引用
收藏
页码:168 / 178
页数:10
相关论文
共 50 条
  • [41] Neuroprotection in acute ischemic stroke - current status
    Auriel, E.
    Bornstein, N. M.
    [J]. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2010, 14 (09) : 2200 - 2202
  • [42] Alamandine Induces Neuroprotection in Ischemic Stroke Models
    Goncalves, Sthefanie C. A.
    Bassi, Beatriz L. T.
    Kangussu, Lucas M.
    Alves, Daniele T.
    Ramos, Lorena K. S.
    Fernandes, Lorena F.
    Alves, Marco T. R.
    Sinisterra, Ruben
    Bruch, Gisele E.
    Santos, Robson A. S.
    Massensini, Andre R.
    Campagnole-Santos, Maria J.
    [J]. CURRENT MEDICINAL CHEMISTRY, 2022, 29 (19) : 3483 - 3498
  • [43] The Role of Citicoline in Neuroprotection and Neurorepair in Ischemic Stroke
    Alvarez-Sabin, Jose
    Roman, Gustavo C.
    [J]. BRAIN SCIENCES, 2013, 3 (03): : 1395 - 1414
  • [44] Investigational Therapies for Ischemic Stroke: Neuroprotection and Neurorecovery
    Preeti Sahota
    Sean I. Savitz
    [J]. Neurotherapeutics, 2011, 8 : 434 - 451
  • [45] Sex Differences in Neuroinflammation and Neuroprotection In Ischemic Stroke
    Spychala, Monica S.
    Honarpisheh, Pedram
    McCullough, Louise D.
    [J]. JOURNAL OF NEUROSCIENCE RESEARCH, 2017, 95 (1-2) : 462 - 471
  • [46] Neuroprotection by pravastatin in acute ischemic stroke in rats
    Berger, Christian
    Xia, Feng
    Maurer, Martin H.
    Schwab, Stefan
    [J]. BRAIN RESEARCH REVIEWS, 2008, 58 (01) : 48 - 56
  • [47] Neuroprotection of acute ischemic stroke: Where are we?
    Fisher, M
    [J]. NEUROSCIENTIST, 1999, 5 (06): : 392 - 401
  • [48] Targeting the Brain: Neuroprotection and Neurorestoration in Ischemic Stroke
    Saver, Jeffrey L.
    [J]. PHARMACOTHERAPY, 2010, 30 (07): : 62S - 69S
  • [49] New possibilities of neuroprotection in the treatment of ischemic stroke
    Skoromets, A. A.
    Stakhovskaya, L. V.
    Belkin, A. A.
    Shekhovtsova, K. V.
    Kerbikov, O. B.
    Burenchev, D. V.
    Gavrilova, O. N.
    Skvortsova, V. I.
    [J]. ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA, 2008, : 32 - 38
  • [50] Neuroprotection for ischemic stroke: Past, present and future
    Ginsberg, Myron D.
    [J]. NEUROPHARMACOLOGY, 2008, 55 (03) : 363 - 389