57 Prophylactic Ibuprofen for The Prevention of Intraventricular Hemorrhage in Preterm Infants: A Multicenter Randomized Study

被引：0
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作者：
C Dani
G Bertini
M Pezzati
V Vangi
P Guerrini
C Martano
F F Rubaltelli
机构：
[1] University of Florence,Department of Medical and Surgical Critical Care
[2] Section of Neonatology,Division of Neonatology
[3] University of Ferrara,Division of Neonatology
[4] University of Turin,undefined
来源：
Pediatric Research | 2004年 / 56卷
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摘要：
Background: Intraventricular hemorrhage (IVH) remains a frequent complication in preterm infants and this point is crucial because the most severe IVH are related to a high risk of neurodevelopmental handicaps. Ibuprofen enhances cerebral blood flow autoregulation and has been shown to protect neurological functions following oxidative stresses in an animal model. For these reasons we hypothesized that the prophylactic use of ibuprofen would reduce the occurrence of IVH.
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页码：473 / 473
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