A multi-centre, double-blind, 12-week, randomized, placebo-controlled trial to assess the efficacy of adjunctive N-Acetylcysteine for treatment-resistant PTSD: a study protocol

被引:0
|
作者
Alice Maier
Anita Dharan
Gina Oliver
Michael Berk
Suzy Redston
Sudie E. Back
Peter Kalivas
Chee Ng
Richard A. Kanaan
机构
[1] University of Melbourne,Department of Psychiatry, Austin Health
[2] University of Melbourne,Department of Psychiatry, The Melbourne Clinic
[3] Deakin University,IMPACT – the Institute for Mental and Physical Health and Clinical Translation, School of Medicine
[4] Barwon Health,Orygen, The National Centre of Excellence in Youth Mental Health, Centre for Youth Mental Health, Florey Institute for Neuroscience and Mental Health and the Department of Psychiatry
[5] The University of Melbourne,Department of Psychiatry and Behavioral Sciences
[6] Austin Health,Department of Neuroscience
[7] Medical University of South Carolina; Ralph H. Johnson VA Medical Center,undefined
[8] Medical University of South Carolina,undefined
[9] Ralph H Johnson VA Medical Center,undefined
来源
关键词
Clinical trial protocol; N-acetyl cysteine; Post-traumatic stress disorder; N-acetyl cysteine; Adjunctive therapy; Randomised clinical trial; Oxidative stress; Biomarker;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] The efficacy of adjunctive N-acetylcysteine in acute bipolar depression: A randomized placebo-controlled study
    Ellegaard, Pernille Kempel
    Licht, Rasmus Wentzer
    Nielsen, Rene Ernst
    Dean, Olivia May
    Berk, Michael
    Poulsen, Henrik Enghusen
    Mohebbi, Mohammadreza
    Nielsen, Connie Thuroee
    JOURNAL OF AFFECTIVE DISORDERS, 2019, 245 : 1043 - 1051
  • [42] Naltrexone versus acamprosate in the treatment of alcohol dependence: a multi-centre, randomized, double-blind, placebo-controlled trial
    Morley, Kirsten C.
    Teesson, Maree
    Reid, Sophie C.
    Sannibale, Claudia
    Thomson, Clare
    Phung, Nghi
    Weltman, Martin
    Bell, James R.
    Richardson, Kylie
    Haber, Paul S.
    ADDICTION, 2006, 101 (10) : 1451 - 1462
  • [43] A Double Blind, Placebo-Controlled, Randomized Trial Of N-Acetylcysteine In Idiopathic Pulmonary Fibrosis
    Raghu, G.
    DeAndrade, J.
    Anstrom, K. J.
    King, T. E.
    Martinez, F. J.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 189
  • [44] N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis
    Conus, Philippe
    Seidman, Larry J.
    Fournier, Margot
    Xin, Lijing
    Cleusix, Martine
    Baumann, Philipp S.
    Ferrari, Carina
    Cousins, Ann
    Alameda, Luis
    Gholam-Rezaee, Mehdi
    Golay, Philippe
    Jenni, Raoul
    Woo, T. -U. Wilson
    Keshavan, Matcheri S.
    Eap, Chin B.
    Wojcik, Joanne
    Cuenod, Michel
    Buclin, Thierry
    Gruetter, Rolf
    Do, Kim Q.
    SCHIZOPHRENIA BULLETIN, 2018, 44 (02) : 317 - 327
  • [45] N acetylcysteine in the treatment of alcohol use disorder: a randomized, double-blind, placebo-controlled trial
    Morley, Kirsten C.
    Peruch, Siena
    Adams, Claire
    Towers, Ellen
    Tremonti, Chris
    Watt, Joshua
    Jamshidi, Nazila
    Haber, Paul S.
    ALCOHOL AND ALCOHOLISM, 2023, 58 (05): : 553 - 560
  • [46] N-acetylcysteine as adjunctive treatment in severe malaria: A randomized, double-blinded placebo-controlled clinical trial
    Charunwatthana, Prakaykaew
    Faiz, M. Abul
    Ruangveerayut, Ronnatrai
    Maude, Richard J.
    Rahman, M. Ridwanur
    Roberts, L. Jackson, II
    Moore, Kevin
    Bin Yunus, Emran
    Hoque, M. Gofranul
    Hasan, Mahatab Uddin
    Lee, Sue J.
    Pukrittayakamee, Sasithon
    Newton, Paul N.
    White, Nicholas J.
    Day, Nicholas P. J.
    Dondorp, Arjen M.
    CRITICAL CARE MEDICINE, 2009, 37 (02) : 516 - 522
  • [47] Levetiracetam as an Adjunctive Treatment for Mania: A Double-Blind, Randomized, Placebo-Controlled Trial
    Keshavarzi, Amir
    Sharifi, Aziz
    Jahangard, Leila
    Soltanian, Alireza
    Bruehl, Annette Beatrix
    Ahmadpanah, Mohammad
    Brand, Serge
    NEUROPSYCHOBIOLOGY, 2022, 81 (03) : 192 - 203
  • [48] Adjunctive use of controlled-release pregabalin in adults with treatment-resistant partial seizures: A double-blind, randomized, placebo-controlled trial
    French, Jacqueline
    Brandt, Christian
    Friedman, Daniel
    Biton, Victor
    Knapp, Lloyd
    Pitman, Verne
    Chew, Marci
    Dubrava, Sarah
    Posner, Holly B.
    EPILEPSIA, 2014, 55 (08) : 1220 - 1228
  • [49] Add-on treatment with N-acetylcysteine for bipolar depression: a 24-week randomized double-blind parallel group placebo-controlled multicentre trial (NACOS-study protocol)
    Pernille Kempel Ellegaard
    Rasmus Wentzer Licht
    Henrik Enghusen Poulsen
    René Ernst Nielsen
    Michael Berk
    Olivia May Dean
    Mohammadreza Mohebbi
    Connie Thuroee Nielsen
    International Journal of Bipolar Disorders, 6
  • [50] Add-on treatment with N-acetylcysteine for bipolar depression: a 24-week randomized double-blind parallel group placebo-controlled multicentre trial (NACOS-study protocol)
    Ellegaard, Pernille Kempel
    Licht, Rasmus Wentzer
    Poulsen, Henrik Enghusen
    Nielsen, Rene Ernst
    Berk, Michael
    Dean, Olivia May
    Mohebbi, Mohammadreza
    Nielsen, Connie Thuroee
    INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS, 2018, 6