Genetic variation in LIN28B is associated with the timing of puberty

被引：0

作者：

Ken K Ong

Cathy E Elks

Shengxu Li

Jing Hua Zhao

Jian'an Luan

Lars B Andersen

Sheila A Bingham

Soren Brage

George Davey Smith

Ulf Ekelund

Christopher J Gillson

Beate Glaser

Jean Golding

Rebecca Hardy

Kay-Tee Khaw

Diana Kuh

Robert Luben

Michele Marcus

Michael A McGeehin

Andrew R Ness

Kate Northstone

Susan M Ring

Carol Rubin

Matthew A Sims

Kijoung Song

David P Strachan

Peter Vollenweider

Gerard Waeber

Dawn M Waterworth

Andrew Wong

Panagiotis Deloukas

Inês Barroso

Vincent Mooser

Ruth J Loos

Nicholas J Wareham

机构：

[1] Medical Research Council (MRC) Epidemiology Unit,Department of Paediatrics

[2] Addenbrooke's Hospital,Department of Social Medicine

[3] Institute of Metabolic Science,Department of Community Based Medicine

[4] Addenbrooke's Hospital,Department of Public Health and Primary Care

[5] University of Cambridge,Department of Epidemiology

[6] Institute of Sport Science and Clinical Biomechanics,Departments of Environmental and Occupational Health

[7] University of Southern Denmark,Department of Oral and Dental Science

[8] MRC Dunn Human Nutrition Unit,Department of Social Medicine

[9] Wellcome Trust/MRC Building,Genetics Division

[10] MRC Centre for Nutritional Epidemiology in Cancer Prevention and Survival,Division of Community Health Sciences

[11] MRC Centre for Causal Analyses in Translational Epidemiology,Department of Internal Medicine

[12] University of Bristol,undefined

[13] School of Health and Medical Sciences,undefined

[14] Örebro University,undefined

[15] Avon Longitudinal Study of Parents and Children (ALSPAC),undefined

[16] University of Bristol,undefined

[17] MRC Unit for Lifelong Health and Ageing,undefined

[18] Institute of Public Health,undefined

[19] University of Cambridge,undefined

[20] National Center for Environmental Health,undefined

[21] Centers for Disease Control and Prevention,undefined

[22] Rollins School of Public Health,undefined

[23] Emory University,undefined

[24] Rollins School of Public Health,undefined

[25] Emory University,undefined

[26] University of Bristol,undefined

[27] ALSPAC,undefined

[28] University of Bristol,undefined

[29] GlaxoSmithKline,undefined

[30] King of Prussia,undefined

[31] St. George's,undefined

[32] University of London,undefined

[33] BH-10 Centre Hospitalier Universitaire Vaudois (CHUV),undefined

[34] Wellcome Trust Sanger Institute,undefined

来源：

Nature Genetics | 2009年 / 41卷

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学科分类号：

摘要：

Ken Ong and colleagues report a genome-wide association study for age at menarche. They find LIN28B associated with age at menarche, as well as several traits related to onset of puberty in both females and males.

引用

页码：729 / 733

页数：4

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