Localized diacylglycerol drives the polarization of the microtubule-organizing center in T cells

被引:0
|
作者
Emily J Quann
Ernesto Merino
Toshiaki Furuta
Morgan Huse
机构
[1] Immunology Program,Department of Biomolecular Science
[2] Memorial Sloan-Kettering Cancer Center,undefined
[3] Toho University,undefined
来源
Nature Immunology | 2009年 / 10卷
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学科分类号
摘要
The reorientation of the T cell microtubule-organizing center toward the antigen-presenting cell enables the directional secretion of cytokines and lytic factors. Huse and colleagues show that this process depends on diacylglycerol.
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页码:627 / 635
页数:8
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