Alkylation of 2-(2,4-dichlorophenyl)-3-cyano-6-methyl-4-(1H-1,2,4-triazol-1-yl)methylpyridine at the methylene group

被引：0
|
作者：
Yan Zhu
Zhengyan Cai
Qun Hao
Weicheng Zhou
机构：
[1] State Key Lab of New Drug & Pharmaceutical Process,
[2] Shanghai Key Lab of Anti-Infectives,undefined
[3] Shanghai Institute of Pharmaceutical Industry,undefined
[4] State Institute of Pharmaceutical Industry,undefined
来源：
Chemistry of Heterocyclic Compounds | 2016年 / 52卷
关键词：
activated methylene compounds; alkyl halides; phenylpyridines; structure–reactivity relationships;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
[graphic not available: see fulltext]
引用
收藏
页码：564 / 569
页数：5
相关论文
共 50 条
  • [31] 1-(4-fluorophenyl)-2-{4-phenyl-5-[(1H-1,2,4-triazol-1-yl) methyl]-4H-1,2,4-triazol-3-ylsulfanyl}ethanone
    Xu, LZ
    Li, K
    Liu, JH
    Zhou, K
    Li, WH
    Hou, BR
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O2338 - O2339
  • [32] (2,4-Difluorophenyl)[1-(1H-1,2,4-triazol-1-yl)cyclopropyl]methanone
    Wu, Chunli
    Lei, Wei
    Ma, Huiyan
    Qiao, Jiabin
    Li, Aixing
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2913 - U286
  • [33] 1-(4-Fluorophenyl)-2-(3-phenylthiazolidin-2-ylidene)-2-(1H-1,2,4-triazol-1-yl)ethanone
    Xu, LZ
    Zhu, CY
    Yu, GP
    Jian, FF
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O1180 - O1181
  • [34] Synthesis, structure and biological activity of 2-{5[(1H-1,2,4-triazol-1-yl)methyl]-4-phenyl-4H-1,2,4-triazol-3-ylthio}-1-arylethanone
    Hu, Zhi-Qiang
    Yang, Ya-Xun
    Zhang, Gong-Sheng
    Li, Kai
    Xu, Liang-Zhong
    CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2007, 27 (03) : 419 - 423
  • [35] 1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethanone
    Guven, Ozden Ozel
    Tahtaci, Hakan
    Coles, Simon J.
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1604 - U3253
  • [36] 1-phenyl-2-(1H-1,2,4-triazol-1-yl)ethanol
    Guven, Ozden Ozel
    Tahtaci, Hakan
    Coles, Simon J.
    Hokelek, Tuncer
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1254 - U1822
  • [37] 1-{[1-(2,4-Dichlorophenyl)-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole
    Xie, Xue-Qun
    Yang, Chun-Long
    Luo, Jin-Xiang
    Li, Qian-Jin
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O2858 - O2859
  • [38] Design, synthesis and antifungal evaluation of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-1H-1,2,4-triazol-5(4H)-one
    Jiang, Yongwei
    Cao, Yongbin
    Zhang, Jun
    Zou, Yan
    Chai, Xiaoyun
    Hu, Honggang
    Zhao, Qingjie
    Wu, Qiuye
    Zhang, Dazhi
    Jiang, Yuanying
    Sun, Qingyan
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2011, 46 (07) : 3135 - 3141
  • [39] Crystal structure of 4-{[(1H-1,2,4-triazol-1-yl)methyl]sulfanyl}phenol
    Zhang, Yong-Le
    Zhang, Chuang
    Guo, Wei
    Wang, Jing
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 : O1106 - +
  • [40] Design and synthesis of 1-(2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl)-2-(1-((methyl(3-(((methylcarbamoyl)oxy)methyl)pyridin-2-yl)carbamoyl)oxy)ethyl)-1H-1,2,4-triazol-2-ium
    Peyton, Lee
    Hashemzadeh, Mehrnoosh
    Gallagher, Scarlett
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
12345