Synthesis and Neurotropic Activity of 8-Amino Derivatives of Condensed Thieno[3,2-d]- and Furo[3,2-d]Pyrimidines

被引：0
|
作者：
S. N. Sirakanyan
A. A. Ovakimyan
A. S. Noravyan
N. S. Minasyan
I. A. Dzhagatspanyan
I. M. Nazaryan
A. G. Akopyan
机构：
[1] National Academy of Sciences of Armenia,Mndjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry
[2] National Academy of Sciences of Armenia,Molecular Structure Research Center, Scientific and Technological Center of Organic and Pharmaceutical Chemistry
来源：
Pharmaceutical Chemistry Journal | 2014年 / 47卷
关键词：
pyrano[3,4-; ]pyridines; thieno[3,2-; ]pyrimidines; furo[3,2-; ]pyrimidines; cyclization; amino derivatives; neurotropic activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New derivatives of pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidines based on 3-chloro derivatives of pyrano[3,4-c]pyridines and pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]furo[3,2-d]pyrimidines based on previously prepared 8-chloro derivatives were synthesized. Studies of the biological activity of the synthesized compounds showed that several of them exhibited neurotropic properties.
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页码：655 / 659
页数：4
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