Amazing T-type calcium channels: updating functional properties in health and disease

被引：0
|
作者：
Bernd Nilius
Emilio Carbone
机构：
[1] KU Leuven,Department of Cellular and Molecular Medicine, Laboratory Ion Channel Research
[2] NIS Center,Department of Drug Science, Laboratory of Cellular & Molecular Neuroscience
[3] CNISM,undefined
[4] University of Torino,undefined
来源：
Pflügers Archiv - European Journal of Physiology | 2014年 / 466卷
关键词：
Voltage-gated ion channels; Calcium channels; Modulation; Recruitment; Antagonist; Animal models; Disease;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
T-type Ca2+ channels have gained, 15 years after cloning, an immense interest as novel players in very unexpected cell functions, and its many relations to diseases have been discovered. This special issue provides a state-of-the-art overview on novel functional properties of T-type Ca2+ channels, unexpected cellular functions, and most importantly will also summarizes and review the involvement of this “tiny, transient” type of Ca2+ channels in several diseases. It is tried to bridge the gap between molecular biophysical properties of T-type Ca2+ channels and diseases providing finally a translational view on this amazing ion channel.
引用
收藏
页码：623 / 626
页数：3
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