KLF5, a new player and new target in the permanently changing set of pancreatic cancer molecular drivers

被引：0
|
作者：
M. V. Zinovyeva
M. B. Kostina
I. P. Chernov
L. G. Kondratyeva
E. D. Sverdlov
机构：
[1] Russian Academy of Sciences,Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry
来源：
Russian Journal of Bioorganic Chemistry | 2016年 / 42卷
关键词：
pancreatic ductal adenocarcinoma; KLF5; carcinogenesis; master genes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Pancreatic cancer is one of the most aggressive tumor types characterized by chemotherapy resistance and high metastatic activity. Recent studies revealed new genes, which are likely to be actively involved in the regulation of the processes occurring in the pancreas, as well as in the development of cancer in this organ. This review is devoted to the description of one of the recently revealed genes, KLF5, which seems to be a promising target for therapeutic intervention in the most widespread type of pancreatic cancer, ductal adenocarcinoma.
引用
收藏
页码：606 / 611
页数：5
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