The complex life of the HIV-1 full-length RNA

被引:0
|
作者
Soto-Rifo, Ricardo [1 ,2 ,3 ]
机构
[1] Univ Chile, Inst Biomed Sci, Fac Med, Lab Mol & Cellular Virol, Santiago, Chile
[2] Univ Chile, Fac Med, HIV AIDS Workgrp, Santiago, Chile
[3] Millennium Inst Immunol & Immunotherapy, Santiago, Chile
关键词
D O I
10.1038/s41579-024-01049-7
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this Journal Club, Ricardo Soto-Rifo discusses a study on intron-containing HIV-1 RNA, revealing its role as a pathogen-associated molecular pattern in myeloid cells, which has implications for immune activation, inflammation and clinical outcomes.
引用
收藏
页码:325 / 325
页数:1
相关论文
共 50 条
  • [31] Expression, purification and characterization of a full-length recombinant HIV-1 Vpu from inclusion bodies
    Njengele, Zikhona
    Kleynhans, Ronel
    Sayed, Yasien
    Mosebi, Salerwe
    PROTEIN EXPRESSION AND PURIFICATION, 2016, 128 : 109 - 114
  • [32] Virtual screening application of a model of full-length HIV-1 integrase complexed with viral DNA
    Liao, Chenzhong
    Karki, Rajeshri G.
    Marchand, Christophe
    Pommier, Yves
    Nicklaus, Marc C.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (19) : 5361 - 5365
  • [33] Near Full-length Genome Characterization of HIV-1 Subtypes Among Drug Users in Kenya
    Zulu, Thando
    Ongeri, Micah
    Ndung'u, Thumbi
    Gounder, Kamini
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2018, 34 : 389 - 389
  • [34] Full-length HIV-1 gag determines protease inhibitor susceptibility within in vitro assays
    Gupta, R. K.
    Kohli, A.
    McCormick, A.
    Towers, G.
    Pillay, D.
    Parry, C. M.
    ANTIVIRAL THERAPY, 2010, 15 : A83 - A83
  • [35] HIV-1 IS TRANS-ACTIVATED BY THE FULL-LENGTH GENE-PRODUCT OF TAT OF HIV-2
    TONG, SE
    BAUR, A
    LU, X
    PECK, E
    PETERLIN, BM
    FASEB JOURNAL, 1992, 6 (05): : A1978 - A1978
  • [36] Analysis of the latent reservoir of a patient infected with HIV under PrEP by single full-length HIV-1 amplification
    Damagnez, M.
    Scholten, S.
    di Cristanziano, V.
    Sierra, S.
    Boehm, M.
    Daeumer, M.
    Thielen, A.
    Kaiser, R.
    Knops, E.
    Heger, E.
    HIV MEDICINE, 2019, 20 : 172 - 172
  • [37] Dual Mechanisms of Translation Initiation of the Full-Length HIV-1 mRNA Contribute to Gag Synthesis
    Monette, Anne
    Valiente-Echeverria, Fernando
    Rivero, Matias
    Cohen, Eric A.
    Lopez-Lastra, Marcelo
    Mouland, Andrew J.
    PLOS ONE, 2013, 8 (07):
  • [38] Synthesis of full-length viral DNA in CD4-positive membrane vesicles exposed to HIV-1 - A model for studies of early stages of the HIV-1 life cycle
    Simm, M
    Pekarskaya, O
    Volsky, DJ
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (45) : 28266 - 28270
  • [39] THE MULTIMERIZATION STATE OF RETROVIRAL RNA IS MODULATED BY AMMONIUM-IONS AND AFFECTS HIV-1 FULL-LENGTH CDNA SYNTHESIS IN-VITRO
    WEISS, S
    HAUSL, G
    FAMULOK, M
    KONIG, B
    NUCLEIC ACIDS RESEARCH, 1993, 21 (21) : 4879 - 4885
  • [40] Rapid, complex adaptation of transmitted HIV-1 full-length genomes in subtype C-infected individuals with differing disease progression
    Abrahams, Melissa-Rose
    Treurnicht, Florette K.
    Ngandu, Nobubelo K.
    Goodier, Sarah A.
    Marais, Jinny C.
    Bredell, Helba
    Thebus, Ruwayhida
    Rosa, Debra de Assis
    Mlisana, Koleka
    Seoighe, Cathal
    Karim, Salim Abdool
    Gray, Clive M.
    Williamson, Carolyn
    AIDS, 2013, 27 (04) : 507 - 518