Mechanism of chromatin remodeling and recovery during passage of RNA polymerase II

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作者
Olga I Kulaeva
Daria A Gaykalova
Nikolai A Pestov
Viktor V Golovastov
Dmitry G Vassylyev
Irina Artsimovitch
Vasily M Studitsky
机构
[1] University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School,Department of Pharmacology
[2] University of Alabama at Birmingham,Department of Biochemistry and Molecular Genetics
[3] Schools of Medicine and Dentistry,Department of Microbiology
[4] The Ohio State University,undefined
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摘要
On specific DNA sequences in vitro, a nucleosome is a polar barrier to RNA polymerase II (Pol II). Further analyses of the sequences underlying this barrier effect now indicate the formation of a loop that would preserve the position of the nucleosome on the DNA, while allowing passage of Pol II.
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页码:1272 / 1278
页数:6
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