Destabilisation of liposomes by bovine serum albumin; Sepharose 2B-Cl experiment

被引：0
|
作者：
A. Michnik
A. Sułkowska
机构：
[1] Silesian University,Medical Physics Department, Institute of Physics
[2] Medical University School,Biophysical Chemistry Department
来源：
Chromatographia | 1997年 / 45卷
关键词：
Gel permeation chromatography; Bovine serum albumin; Stability of liposomes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The stability of liposomes (2∶1 egg yolk lecithin:cholesterol, mole ratio; diameter about 100 nm) at increasing bovine serum albumin (BSA) concentration was study. The influence of introducing positive or negative charge to the liposomal bilayers was tested. The results indicated appreciable destructive effects of serum albumin on the liposomal membranes of neutral and negatively charged liposomes. Near-physiological concentration (30 mg mL−1) of albumin dissolved more then 50% of liposomes.
引用
收藏
页码：155 / 157
页数：2
相关论文
共 50 条
  • [1] Destabilisation of liposomes by bovine serum albumin; Sepharose 2B-Cl experiment.
    Michnik, A
    Sulkowska, A
    [J]. CHROMATOGRAPHIA, 1997, 45 (1) : 155 - 157
  • [2] THE ADSORPTION OF BOVINE SERUM-ALBUMIN BY LIPOSOMES
    LAW, SL
    LO, WY
    PAI, SH
    TEH, GW
    KOU, FY
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1986, 32 (2-3) : 237 - 241
  • [3] Immunoprecipitation of serum albumin with protein A-Sepharose - A biochemistry laboratory experiment
    Bohinski, RC
    [J]. JOURNAL OF CHEMICAL EDUCATION, 2000, 77 (11) : 1460 - 1462
  • [4] COMPLEXING OF THE BOVINE SERUM-ALBUMIN WITH PHOSPHATIDYL CHOLINE LIPOSOMES
    LEBED, OI
    PRIMAK, RG
    TISHCHENKO, RI
    [J]. UKRAINSKII BIOKHIMICHESKII ZHURNAL, 1989, 61 (03): : 101 - 106
  • [5] THE ELECTROKINETIC BEHAVIOR OF LIPOSOMES ADSORBED WITH BOVINE SERUM-ALBUMIN
    LAW, SL
    LO, WY
    PAI, SH
    TEH, GW
    [J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1988, 43 (03) : 257 - 260
  • [6] TOPOLOGICAL DISTRIBUTION OF BOVINE SERUM-ALBUMIN IN MULTILAMELLAR AND UNILAMELLAR LIPOSOMES
    YUNG, B
    SHEK, PN
    STANACEV, NZ
    [J]. CHEMISTRY AND PHYSICS OF LIPIDS, 1985, 37 (03) : 283 - 295
  • [7] Effects of lysozyme and bovine serum albumin on membrane characteristics of dipalmitoylphosphatidylglycerol liposomes
    Tsunoda, T
    Imura, T
    Kadota, M
    Yamazaki, T
    Yamauchi, H
    Kwon, KO
    Yokoyama, S
    Sakai, H
    Abe, M
    [J]. COLLOIDS AND SURFACES B-BIOINTERFACES, 2001, 20 (02) : 155 - 163
  • [8] Behaviour of liposomes loaded with bovine serum albumin during in vitro digestion
    Liu, Weilin
    Ye, Aigian
    Liu, Wei
    Liu, Chengmei
    Han, Jianzhong
    Singh, Harjinder
    [J]. FOOD CHEMISTRY, 2015, 175 : 16 - 24
  • [9] DSC and Raman study on the effect of lysozyme and bovine serum albumin on phospholipids liposomes
    Di Foggia, M.
    Bonora, S.
    Tugnoli, V.
    [J]. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 2013, 111 (03) : 1871 - 1880
  • [10] DSC and Raman study on the effect of lysozyme and bovine serum albumin on phospholipids liposomes
    M. Di Foggia
    S. Bonora
    V. Tugnoli
    [J]. Journal of Thermal Analysis and Calorimetry, 2013, 111 : 1871 - 1880
12345