FR209602 and Related Compounds, Novel Antifungal Lipopeptides from Coleophoma crateriformis No. 738I. Taxonomy, Fermentation, Isolation and Physico-chemical Properties

被引:0
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作者
Ryuichi Kanasaki
Kazutoshi Sakamoto
Michizane Hashimoto
Shigehiro Takase
Yasuhisa Tsurumi
Akihiko Fujie
Motohiro Hino
Seiji Hashimoto
Yasuhiro Hori
机构
[1] Fermentation Research Laboratories,
[2] Fujisawa Pharmaceutical Co.,undefined
[3] Ltd.,undefined
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关键词
FR209602; FR209603; FR209604; antifungal; 1,3-β-glucan synthesis;
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摘要
Novel antifungal lipopeptides, FR209602, FR209603 and FR209604, were isolated from the fermentation broth of a fungal strain No. 738 which was identified as Coleophoma crateriformis from morphological and physiological characteristics. The antibiotics were purified by solvent extraction, HP-20, YMC-ODS and silica gel column chromatography and lyophilization. These compounds were structurally similar to FR901379 previously reported by ourselves which had a sulfate residue in the cyclic peptide portion.
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页码:137 / 144
页数:7
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