Association of NR1I2, CYP3A5 and ABCB1 genetic polymorphisms with variability of temsirolimus pharmacokinetics and toxicity in patients with metastatic bladder cancer

被引:0
|
作者
Litaty C. Mbatchi
Matthieu Gassiot
Philippe Pourquier
Alejando Goberna
Hakim Mahammedi
Loic Mourey
Florence Joly
Serge Lumbroso
Alexandre Evrard
Nadine Houede
机构
[1] CHU Nîmes,Laboratoire de Biochimie et Biologie Moléculaire
[2] Hôpital Carémeau,Laboratoire de Pharmacocinétique, Faculté de Pharmacie
[3] IRCM,Département de Recherche Clinique et d’Epidémiologie
[4] Institut de Recherche en Cancérologie de Montpellier,Département d’Oncologie Médicale
[5] INSERM U1194,Département d’Oncologie Médicale
[6] Université de Montpellier,Département d’Oncologie Médicale
[7] Institut Bergonié,Département d’Oncologie Médicale
[8] Centre Jean Perrin,undefined
[9] IUCT Oncopole,undefined
[10] Centre François Baclesse,undefined
[11] CHU Nîmes,undefined
[12] Hôpital Carémeau,undefined
来源
关键词
Temsirolimus; Pharmacogenetics; NR1I2; CYP3A5; ABCB1; Pharmacokinetics;
D O I
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中图分类号
学科分类号
摘要
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页码:653 / 659
页数:6
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