Two Isoforms of the Human Cyclin C Gene are Expressed Differentially Suggesting that they May Have Distinct Functions

被引：0

作者：

R. L. Katona

P. Loyer

Sarah K. Roby

Jill M. Lahti

机构：

[1] Department of Genetics and Tumor Cell Biology,Institute of Genetics, Biological Research Center

[2] Hungarian Academy of Sciences,undefined

来源：

Acta Biologica Hungarica | 2007年 / 58卷

关键词：

Cyclin C; real-time PCR; transcription; cell cycle; isoforms;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Cyclin C is a highly conserved protein that is involved in divergent cellular processes. The exact roles of its isoforms are presently not very well defined and it is possible that there is a functional divergence amongst them. We therefore sought to assess the expression pattern of cyclin C1 and C2 isoforms in various human tissues and in cell cycle by using real-time PCR experiments. Our findings strongly suggest that the C2 isoform may play a presently unexplored and important role in mammalian testis and probably this isoform is the one that is mainly implicated in cell cycle regulation.

引用

页码：133 / 137

页数：4

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