Disease progression in recurrent glioblastoma patients treated with the VEGFR inhibitor axitinib is associated with increased regulatory T cell numbers and T cell exhaustion

被引：0
|
作者：
Stephanie Du Four
Sarah K. Maenhout
Daphné Benteyn
Brenda De Keersmaecker
Johnny Duerinck
Kris Thielemans
Bart Neyns
Joeri L. Aerts
机构：
[1] Vrije Universiteit Brussel,Laboratory of Molecular and Cellular Therapy
[2] Universitair Ziekenhuis Brussel,Department of Medical Oncology
[3] Universitair Ziekenhuis Brussel,Department of Neurosurgery
来源：
Cancer Immunology, Immunotherapy | 2016年 / 65卷
关键词：
Glioblastoma; Antiangiogenesis; Axitinib; Regulatory T cells; Inhibitory molecules;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：727 / 740
页数：13
相关论文
共 50 条
  • [21] Tetanus toxoid pre-conditioning in recurrent glioblastoma treated with dendritic cell immunotherapy is associated to CD8+T cell response
    Eoli, Marica
    Corbetta, Cristina
    Cuccarini, Valeria
    Anghileri, Elena
    Frigerio, Simona
    Tardini, Maria
    Pollo, Bianca
    Antozzi, Carlo
    Bruzzone, Maria Grazia
    Pellegatta, Serena
    Finocchiaro, Gaetano
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [22] Analysis of regulatory T cell populations in patients with autoimmune disease
    Bonelli, M.
    Savitskaya, A.
    v. Dalwigk, K.
    Rapp, A.
    Smolen, J. S.
    Scheinecker, C.
    ANNALS OF THE RHEUMATIC DISEASES, 2007, 66 : A38 - A39
  • [23] Peripheral T cell responses in glioblastoma patients are associated with an improved survival
    Herold-Mende, C.
    Mossemann, J.
    Jungk, C.
    Ahmadi, R.
    Capper, D.
    Von Deimling, A.
    Unterberg, A.
    Beckhove, P.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S218 - S218
  • [24] PERIPHERAL T CELL RESPONSES IN GLIOBLASTOMA PATIENTS ARE ASSOCIATED WITH AN IMPROVED SURVIVAL
    Herold-Mende, C. C.
    Mossemann, J.
    Jungk, C.
    Ahmadi, R.
    Unterberg, A.
    Capper, D.
    vonDeimling, A.
    Beckhove, P.
    NEURO-ONCOLOGY, 2014, 16
  • [25] T-Cell Senescence and Exhaustion Are Associated with Interval Progression of Multiple Myeloma before Autologous Hematopoietic Cell Transplant
    Bao, Alicia
    Kudalkar, Ruchi
    Rodriguez, Jose
    Zhao, Qiuhong
    Sharma, Nidhi
    Bumma, Naresh
    Devarakonda, Srinivas
    Khan, Abdullah
    Rosko, Ashley E.
    Umyarova, Elvira
    Benson, Don M., Jr.
    Cottini, Francesca
    BLOOD, 2022, 140 : 7257 - 7258
  • [26] Increased circulating level of interleukin-6 and CD8+ T cell exhaustion are associated with progression of COVID-19
    Peng-Hui Yang
    Yi-Bo Ding
    Zhe Xu
    Rui Pu
    Ping Li
    Jin Yan
    Ji-Luo Liu
    Fan-Ping Meng
    Lei Huang
    Lei Shi
    Tian-Jun Jiang
    En-Qiang Qin
    Min Zhao
    Da-Wei Zhang
    Peng Zhao
    Ling-Xiang Yu
    Zhao-Hai Wang
    Zhi-Xian Hong
    Zhao-Hui Xiao
    Qing Xi
    De-Xi Zhao
    Peng Yu
    Cai-Zhong Zhu
    Zhu Chen
    Shao-Geng Zhang
    Jun-Sheng Ji
    Fu-Sheng Wang
    Guang-Wen Cao
    Infectious Diseases of Poverty, 9
  • [27] Increased antibody levels against gut commensals are associated with regulatory T cell defect in patients with APECED
    Hetemaki, I.
    Jarva, H.
    Tervo, H.
    Bratland, E.
    Kisand, K.
    Peterson, P.
    Arstila, T. P.
    IMMUNOLOGY, 2012, 137 : 421 - 421
  • [28] Increased circulating level of interleukin-6 and CD8+ T cell exhaustion are associated with progression of COVID-19
    Yang, Peng-Hui
    Ding, Yi-Bo
    Xu, Zhe
    Pu, Rui
    Li, Ping
    Yan, Jin
    Liu, Ji-Luo
    Meng, Fan-Ping
    Huang, Lei
    Shi, Lei
    Jiang, Tian-Jun
    Qin, En-Qiang
    Zhao, Min
    Zhang, Da-Wei
    Zhao, Peng
    Yu, Ling-Xiang
    Wang, Zhao-Hai
    Hong, Zhi-Xian
    Xiao, Zhao-Hui
    Xi, Qing
    Zhao, De-Xi
    Yu, Peng
    Zhu, Cai-Zhong
    Chen, Zhu
    Zhang, Shao-Geng
    Ji, Jun-Sheng
    Wang, Fu-Sheng
    Cao, Guang-Wen
    INFECTIOUS DISEASES OF POVERTY, 2020, 9 (01)
  • [29] Patients with HIV-associated cancers have evidence of increased T cell dysfunction and exhaustion prior to cancer diagnosis
    Chaudhary, Omkar
    Trotta, Diane
    Wang, Kaicheng
    Wang, Xun
    Chu, Xiuping
    Bradley, Chip
    Okulicz, Jason
    Maves, Ryan C.
    Kronmann, Karl
    Schofield, Christina M.
    Blaylock, Jason M.
    Deng, Yanhong
    Schalper, Kurt A.
    Kaech, Susan M.
    Agan, Brian
    Ganesan, Anuradha
    Emu, Brinda
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 (04)
  • [30] T cell exhaustion is associated with cognitive status and amyloid accumulation in Alzheimer's disease
    Grayson, Jason M.
    Short, Samantha M.
    Lee, C. Jiah
    Park, Nuri
    Marsac, Caitlyn
    Sette, Alessandro
    Lindestam Arlehamn, Cecillia S.
    Leng, Xiaoyan I.
    Lockhart, Samuel N.
    Craft, Suzanne
    SCIENTIFIC REPORTS, 2023, 13 (01)
12345