A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors

被引：0
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作者：
Hiroshi Fukamachi
Seon-Kyu Kim
Jiwon Koh
Hye Seung Lee
Yasushi Sasaki
Kentaro Yamashita
Taketo Nishikawaji
Shu Shimada
Yoshimitsu Akiyama
Sun-ju Byeon
Dong-Hyuck Bae
Keisuke Okuno
Masatoshi Nakagawa
Toshiro Tanioka
Mikito Inokuchi
Hiroshi Kawachi
Kiichiro Tsuchiya
Kazuyuki Kojima
Takashi Tokino
Yoshinobu Eishi
Yong Sung Kim
Woo Ho Kim
Yasuhito Yuasa
Shinji Tanaka
机构：
[1] Tokyo Medical and Dental University,Department of Molecular Oncology, Graduate School of Medical and Dental Sciences
[2] Korea Research Institute of Bioscience and Biotechnology,Personalized Genomic Medicine Research Center
[3] Seoul National University Bundang Hospital,Department of Pathology
[4] Research Institute for Frontier Medicine,Medical Genome Sciences
[5] Sapporo Medical University School of Medicine,Department of Gastroenterology and Hepatology
[6] Sapporo Medical University School of Medicine,Department of Pathology
[7] Seoul National University College of Medicine,Genome Editing Research Center
[8] Korea Research Institute of Bioscience & Biotechnology,Department of Gastrointestinal Surgery, Graduate School of Medical and Dental Sciences
[9] Tokyo Medical and Dental University,Department of Human Pathology, Graduate School of Medical and Dental Sciences
[10] Tokyo Medical and Dental University,Department of Gastroenterology and Hepatology
[11] Tokyo Medical and Dental University,Center of Minimally Invasive Surgery, Graduate School of Medical and Dental Sciences
[12] Tokyo Medical and Dental University,Present Address: Division of Cancer Biology and Therapeutics
[13] Miyagi Cancer Center Research Institute,Present Address: Department of Pathology
[14] The Cancer Institute Hospital of the Japanese Foundation for Cancer Research,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 38卷
关键词：
Diffuse-type gastric cancer; mTOR inhibitor; Temsirolimus; PIK3CA; Microsatellite unstable; Immune checkpoint inhibitor; PD-L1; Patient-derived xenograft; Primary culture;
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