A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors

被引：0

作者：

Hiroshi Fukamachi

Seon-Kyu Kim

Jiwon Koh

Hye Seung Lee

Yasushi Sasaki

Kentaro Yamashita

Taketo Nishikawaji

Shu Shimada

Yoshimitsu Akiyama

Sun-ju Byeon

Dong-Hyuck Bae

Keisuke Okuno

Masatoshi Nakagawa

Toshiro Tanioka

Mikito Inokuchi

Hiroshi Kawachi

Kiichiro Tsuchiya

Kazuyuki Kojima

Takashi Tokino

Yoshinobu Eishi

Yong Sung Kim

Woo Ho Kim

Yasuhito Yuasa

Shinji Tanaka

机构：

[1] Tokyo Medical and Dental University,Department of Molecular Oncology, Graduate School of Medical and Dental Sciences

[2] Korea Research Institute of Bioscience and Biotechnology,Personalized Genomic Medicine Research Center

[3] Seoul National University Bundang Hospital,Department of Pathology

[4] Research Institute for Frontier Medicine,Medical Genome Sciences

[5] Sapporo Medical University School of Medicine,Department of Gastroenterology and Hepatology

[6] Sapporo Medical University School of Medicine,Department of Pathology

[7] Seoul National University College of Medicine,Genome Editing Research Center

[8] Korea Research Institute of Bioscience & Biotechnology,Department of Gastrointestinal Surgery, Graduate School of Medical and Dental Sciences

[9] Tokyo Medical and Dental University,Department of Human Pathology, Graduate School of Medical and Dental Sciences

[10] Tokyo Medical and Dental University,Department of Gastroenterology and Hepatology

[11] Tokyo Medical and Dental University,Center of Minimally Invasive Surgery, Graduate School of Medical and Dental Sciences

[12] Tokyo Medical and Dental University,Present Address: Division of Cancer Biology and Therapeutics

[13] Miyagi Cancer Center Research Institute,Present Address: Department of Pathology

[14] The Cancer Institute Hospital of the Japanese Foundation for Cancer Research,undefined

来源：

Journal of Experimental & Clinical Cancer Research | / 38卷

关键词：

Diffuse-type gastric cancer; mTOR inhibitor; Temsirolimus; PIK3CA; Microsatellite unstable; Immune checkpoint inhibitor; PD-L1; Patient-derived xenograft; Primary culture;

D O I：

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中图分类号：

学科分类号：

摘要：

引用

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[1] A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors
Fukamachi, Hiroshi
Kim, Seon-Kyu
Koh, Jiwon
Lee, Hye Seung
Sasaki, Yasushi
Yamashita, Kentaro
Nishikawaji, Taketo
Shimada, Shu
Akiyama, Yoshimitsu
Byeon, Sun-ju
Bae, Dong-Hyuck
Okuno, Keisuke
Nakagawa, Masatoshi
Tanioka, Toshiro
Inokuchi, Mikito
Kawachi, Hiroshi
Tsuchiya, Kiichiro
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Eishi, Yoshinobu
Kim, Yong Sung
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JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 38
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