Genome structural variation and sporadic disease traits

被引：0
|
作者：
James R Lupski
机构：
[1] Baylor College of Medicine and Texas Children's Hospital,Department of Molecular and Human Genetics and the Department of Pediatrics
来源：
Nature Genetics | 2006年 / 38卷
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摘要：
Many submicroscopic genomic rearrangements have been robustly associated with well-defined clinical syndromes. Three papers in this issue once again illustrate how underlying genomic architecture can catalyze rearrangement causing sporadic disease, and they further suggest that widespread clinical implementation of high-resolution genome analysis may identify the cause of traits previously intractable to conventional genetic analyses.
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页码：974 / 976
页数：2
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