Synthesis of pyrrolo[2,3-d]pyrimidines with 3-amino-2-hydroxypropyl substituents

被引：0
|
作者：
L. V. Muzychka
E. V. Verves
I. O. Yaremchuk
O. B. Smolii
机构：
[1] Ukraine National Academy of Sciences,Institute of Bioorganic and Petroleum Chemistry
来源：
Chemistry of Heterocyclic Compounds | 2012年 / 48卷
关键词：
pyrimido[5',4':4,5]pyrrolo[2,1-; ][1,4]oxazines; pyrrolo[2,3-; ]pyrimidines; bromolacto-nization;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A novel route has been found for the synthesis of pyrimido[5',4':4,5]pyrrolo[2,1-c][1,4]oxazines. They are promising reagents for the preparation of pyrrolo[2,3-d]pyrimidine-6-carboxylic acid amides which contain a 3-amino-2-hydroxypropyl substituent in position 7 of the heterocyclic ring.
引用
收藏
页码：481 / 487
页数：6
相关论文
共 50 条
  • [21] SYNTHESIS OF THIOPYRANO [2,3-D]PYRIMIDINES AND THIENO [2,3-D]PYRIMIDINES
    SANTILLI, AA
    SCOTESE, AC
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1977, 14 (03) : 361 - 365
  • [22] SYNTHESIS OF THIOPYRANO[2,3-D]PYRIMIDINES AND THIENO[2,3-D]PYRIMIDINES
    ASSY, MG
    ELKAFRAWY, A
    HASSANIEN, MM
    POLISH JOURNAL OF CHEMISTRY, 1995, 69 (06) : 887 - 891
  • [23] The antiinfluenza activity of pyrrolo[2,3-d]pyrimidines
    Sznaidman, ML
    Meade, EA
    Beauchamp, LM
    Russell, S
    Tisdale, M
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1996, 6 (05) : 565 - 568
  • [24] PYRROLO[2,3-D]PYRIMIDINES .1. SYNTHESIS OF NOVEL PYRROLO[2,3-D] PYRIMIDINE-DERIVATIVES WITH ANTIMICROBIAL ACTIVITY
    ELBAYOUKI, KAM
    BASYOUNI, WM
    HOSNI, H
    ELDEEN, AS
    JOURNAL OF CHEMICAL RESEARCH-S, 1995, (08): : 314 - 315
  • [25] IMPROVED PROCEDURES FOR THE SYNTHESES OF PYRIDO[2,3-D]PYRIMIDINES AND PYRROLO[2,3-D]PYRIMIDINES, AND RIBOSIDES THEREOF
    ITOH, T
    MELIKOHANJANIAN, RG
    ISHIKAWA, I
    KAWAHARA, N
    MIZUNO, Y
    HONMA, Y
    HOZUMI, M
    OGURA, H
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1989, 37 (12) : 3184 - 3190
  • [26] Synthesis of pyrrolo[2,3-d]pyrimidines via cyclocondensation of β-alkoxy- and β-amino-α-bromoaldehydes
    Barnett, CJ
    Grubb, LM
    TETRAHEDRON LETTERS, 2000, 41 (50) : 9741 - 9745
  • [27] A convenient synthesis of pyrrolo[2,3-b]pyridines and pyrido[2′,3′:5,4]pyrrolo[2,3-d]pyrimidines
    Shawkat A. Abdel-Mohsen
    Ahmed A. Geies
    Monatshefte für Chemie - Chemical Monthly, 2008, 139
  • [28] A convenient synthesis of pyrrolo[2,3-b]pyridines and pyrido[2′,3′:5,4]pyrrolo[2,3-d]pyrimidines
    Abdel-Mohsen, Shawkat A.
    Geies, Ahmed A.
    MONATSHEFTE FUR CHEMIE, 2008, 139 (10): : 1233 - 1240
  • [29] PYRIDO[2,3-D]PYRIMIDINES .8. SYNTHESIS OF PYRROLO(2',3'/4,5)PYRIDO[2,3-D]PIRIMIDINES
    BISTRYAKOVA, ID
    SMIRNOVA, NM
    SAFONOVA, TS
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (06): : 800 - 803
  • [30] Synthesis of Some New Pyrimidines and Pyrrolo [2,3-d] Pyrimidines as Potential Antimicrobial Agents
    Nofal, Z. M.
    Fahmy, H. H.
    Zarie, E. S.
    Hamdy, A. A.
    EGYPTIAN JOURNAL OF CHEMISTRY, 2011, 54 (05): : 595 - 608
12345