Controversies in the Role of Radiotherapy in the Treatment of Pediatric Hodgkin Lymphoma

被引：0
|
作者：
Meret Henry
Süreyya Savaşan
机构：
[1] Children’s Hospital of Michigan,Division of Hematology/Oncology, Department of Pediatrics
[2] Wayne State University,Children’s Hospital of Michigan, Blood and Marrow Transplantation Program, Barbara Ann Karmanos Cancer Center
来源：
The Indian Journal of Pediatrics | 2013年 / 80卷
关键词：
Hodgkin lymphoma; Radiation therapy; Pediatric;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Hodgkin lymphoma in children is a highly curable malignancy with current approaches utilizing combined modality therapy and a risk-adapted approach. The combination of anthracyclines, bleomycin, and radiotherapy, as well as other alkylating agents, are significant risk factors for secondary malignancies and cardiopulmonary toxicity. Therefore, current strategies aim to optimize cure rates while minimizing late effects. The role of radiotherapy has been examined in recent pediatric trials, with varying results. However, they provide evidence, as a whole, for the omission of radiotherapy for a subgroup of patients, without compromising outcomes.
引用
收藏
页码：863 / 869
页数：6
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