Hydrogenation N-alkylation of α-alanyl-α-proline with ethyl 2-oxo-4-phenylbutanoate on organometallic catalysts

被引:0
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作者
M. G. Abdullaev
机构
[1] Dagestan State University,Department of Chemistry
来源
Russian Chemical Bulletin | 2020年 / 69卷
关键词
hydroalkylation; α-alanyl-α-proline; ethyl 2-oxo-4-phenylbutanoate; organometallic catalysts;
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摘要
New nickel- and palladium-containing catalysts for reductive N-alkylation of α-alanyl-α-proline dipeptide with ethyl 2-oxo-4-phenylbutanoate have been investigated. Based on the empirical data obtained, the optimal scheme for the catalytic synthesis of enalapril was proposed.
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页码:1923 / 1927
页数:4
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