Methyltransferase-like 3 (METTL3) mediated N6-methyladenosine (m6A) modifications facilitate mir-25-3p maturation to promote gastrointestinal stromal tumors (GISTs) progression

被引：0
|
作者：
Kun Qian
Wei Xu
Xiaoyao Xia
Jinhuo Ding
机构：
[1] Shangrao People’s Hospital,Department of General Surgery
[2] The Second Affiliated Hospital of Nanchang University,Department of Gastrointestinal Surgery, Colorectal Tumor Minimally Invasive Center
[3] Shangrao People’s Hospital,Department of General Surgery
来源：
Genes & Genomics | 2022年 / 44卷
关键词：
Methyltransferase-like 3; N6-methyladenosine; Gastrointestinal stromal tumors; miR-25-3p;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1519 / 1530
页数：11
相关论文
共 50 条
  • [21] METTL3 (Methyltransferase Like 3)-Dependent N6-Methyladenosine Modification on Braf mRNA Promotes Macrophage Inflammatory Response and Atherosclerosis in Mice
    Li, Qian
    Yu, Liwen
    Gao, Amy
    Ren, Ruiqing
    Zhang, Jianlin
    Cao, Lei
    Wang, Xiaohong
    Liu, Yapeng
    Qi, Wenqian
    Cai, Liangyu
    Li, Wei
    Wang, Weiwei
    Guo, Xiaobin
    Su, Guohai
    Yu, Xiao
    Zhang, Jie
    Xi, Bo
    Zhang, Yun
    Zhang, Meng
    Zhang, Cheng
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 43 (05) : 755 - 773
  • [22] N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression
    Zhaowei Lin
    Tao Jiang
    Wei Zheng
    Jiayuan Zhang
    Anan Li
    Chao Lu
    Wengang Liu
    Cell Communication and Signaling, 21
  • [23] Identification of Key Genes Mediated by N6-Methyladenosine Methyltransferase METTL3 in Ischemic Stroke via Bioinformatics Analysis and Experiments
    Liang, Tian
    Zhu, Lulu
    Yang, Jialei
    Huang, Xiaolan
    Lv, Miao
    Liu, Shengying
    Wen, Zheng
    Su, Li
    Zhou, Lifang
    MOLECULAR BIOTECHNOLOGY, 2025, 67 (01) : 160 - 174
  • [24] The RNA N6-Methyladenosine Methyltransferase METTL3 Promotes the Progression of Kidney Cancer via N6-Methyladenosine-Dependent Translational Enhancement of ABCD1
    Shi, Yue
    Dou, Yanliang
    Zhang, Jianye
    Qi, Jie
    Xin, Zijuan
    Zhang, Mingxin
    Xiao, Yu
    Ci, Weimin
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021, 9
  • [25] N6-methyladenosine modifications enhance enterovirus 71 ORF translation through METTL3 cytoplasmic distribution
    Yao, Min
    Dong, Yangchao
    Wang, Yuan
    Liu, He
    Ma, Hongwei
    Zhang, Hui
    Zhang, Liang
    Cheng, Linfeng
    Lv, Xin
    Xu, Zhikai
    Zhang, Fanglin
    Lei, Yingfeng
    Ye, Wei
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 527 (01) : 297 - 304
  • [26] Progression of Thyroid Carcinoma Is Promoted by the m6A Methyltransferase METTL3 Through Regulating m6A Methylation on TCF1
    Wang, Kejin
    Jiang, Lin
    Zhang, Yan
    Chen, Chao
    ONCOTARGETS AND THERAPY, 2020, 13 : 1605 - 1612
  • [27] METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma
    Zhijin Zhang
    Jun Fu
    Yuhao Zhang
    Xianju Qin
    Yuexia Wang
    Chungen Xing
    BMC Gastroenterology, 23
  • [28] METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progression of stomach adenocarcinoma
    Zhang, Zhijin
    Fu, Jun
    Zhang, Yuhao
    Qin, Xianju
    Wang, Yuexia
    Xing, Chungen
    BMC GASTROENTEROLOGY, 2023, 23 (01)
  • [29] Methyltransferase-Like 3-Mediated N6-Methyladenosine Modification on RNAs: A Novel Perspective for the Pathogenesis and Treatment of Bone Diseases
    Xiao, Dongqiong
    Zhang, Deshuang
    Qu, Yi
    Su, Xiaojuan
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2025, 29 (05)
  • [30] N6-methyladenosine METTL3 promotes the breast cancer progression via targeting Bcl-2
    Wang, Hong
    Xu, Bei
    Shi, Jun
    GENE, 2020, 722
12345