Fishing for missing heritability in IBD

被引：0
|
作者：
Michael Pack
机构：
[1] Perelman School of Medicine,Department of Medicine and Cell and Developmental Biology
[2] University of Pennsylvania,undefined
来源：
Nature Reviews Gastroenterology & Hepatology | 2015年 / 12卷
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学科分类号：
摘要：
A genetic predisposition to IBD is widely accepted; however IBD heritability is dependent on more than the simple additive risk of genetic variants. In a new study using zebrafish, convincing evidence is presented that alterations in the epigenetic regulation of TNF might contribute to the 'missing heritability' of IBD.
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页码：318 / 320
页数：2
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