Stem cell therapy for amyotrophic lateral sclerosis

被引：13
|
作者：
Mao Z. [1 ]
Zhang S. [1 ]
Chen H. [2 ]
机构：
[1] Huazhong University of Science and Technology, Department of Neurology of Tongji Hospital, Tongji Medical College, Wuhan
[2] Huazhong University of Science and Technology, Department of Rehabilitation of Tongji Hospital, Tongji Medical College, Wuhan
来源：
Cell Regeneration | / 4卷 / 1期
基金：
中国国家自然科学基金;
关键词：
Amyotrophic lateral sclerosis; Cell transplantation; Clinical translation; Stem cells;
D O I：
10.1186/s13619-015-0026-7
中图分类号：
学科分类号：
摘要：
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by the loss of motor neurons. Currently, no effective therapy is available to treat ALS, except for Riluzole, which has only limited clinical benefits. Stem-cell-based therapy has been intensively and extensively studied as a potential novel treatment strategy for ALS and has been shown to be effective, at least to some extent. In this article, we will review the current state of research on the use of stem cell therapy in the treatment of ALS and discuss the most promising stem cells for the treatment of ALS. © 2015 Mao et al.
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