Sulf2 mediates the effects of TNF in RASFs

被引：0
|
作者：
Sarah Onuora
机构：
[1] Nature Reviews Rheumatology,
来源：
Nature Reviews Rheumatology | 2022年 / 18卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
New research suggests that the pro-inflammatory effects of TNF on rheumatoid arthritis synovial fibroblasts are mediated by extracellular sulfatase Sulf2, which could present a novel target for treatment.
引用
收藏
页码：613 / 613
相关论文
共 50 条
  • [41] Organ-specific Sulfation Patterns of Heparan Sulfate Generated by Extracellular Sulfatases Sulf1 and Sulf2 in Mice
    Nagamine, Satoshi
    Tamba, Michiko
    Ishimine, Hisako
    Araki, Kota
    Shiomi, Kensuke
    Okada, Takuya
    Ohto, Tatsuyuki
    Kunita, Satoshi
    Takahashi, Satoru
    Wismans, Ronnie G. P.
    van Kuppevelt, Toin H.
    Masu, Masayuki
    Keino-Masu, Kazuko
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (12) : 9579 - 9590
  • [42] Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development
    Ratzka, Andreas
    Kalus, Ina
    Moser, Markus
    Dierks, Thomas
    Mundlos, Stefan
    Vortkamp, Andrea
    DEVELOPMENTAL DYNAMICS, 2008, 237 (02) : 339 - 353
  • [43] Purification and in vitro Characterization of Human Extracellular Heparan 6-O-Endo-Sulfatases Sulf1 and Sulf2
    Aljuhani, Reem
    Benicky, Julius
    Zhang, Lihua
    Liu, Jian
    Pomin, Vitor
    Goldman, Radoslav
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2024, 300 (03) : S294 - S295
  • [44] Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck
    Flowers, Sarah A.
    Zhou, Xin
    Wu, Jing
    Wang, Yiwen
    Makambi, Kepher
    Kallakury, Bhaskar V.
    Singer, Mark S.
    Rosen, Steven D.
    Davidson, Bruce
    Goldman, Radoslav
    ONCOTARGET, 2016, 7 (28) : 43177 - 43187
  • [45] SULF2 expression is prognostic for overall survival in Head and Neck Squamous Cell Carcinoma
    Yang, Yang
    Ahn, Jaeil
    Kallakury, Bhaskar V.
    Brnakova, Zuzana
    Davidson, Bruce J.
    Goldman, Radoslav
    GLYCOBIOLOGY, 2018, 28 (12) : 1068 - 1069
  • [46] Correlation between the methylation of SULF2 and WRN promoter and the irinotecan chemosensitivity in gastric cancer
    Lin Wang
    Li Xie
    Jun Wang
    Jie Shen
    Baorui Liu
    BMC Gastroenterology, 13
  • [47] SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis
    Singer, Mark S.
    Phillips, Joanna J.
    Lemjabbar-Alaoui, Hassan
    Wang, Yang Qing
    Wu, Jing
    Goldman, Radoslav
    Rosen, Steven D.
    CLINICA CHIMICA ACTA, 2015, 440 : 72 - 78
  • [48] Up-regulation of SULF2 is associated with a poor prognosis of patients with prostate cancer
    Lu, Jianlei
    Zhong, Feng
    Sun, Beibei
    Wang, Chao
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 9 (03): : 3612 - 3617
  • [49] Sulf2 gene is alternatively spliced in mammalian developing and tumour tissues with functional implications
    Gill, Rai B. S.
    Day, Amy
    Barstow, Amy
    Liu, Hongxiang
    Zaman, Gul
    Dhoot, Gurtej K.
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2011, 414 (03) : 468 - 473
  • [50] Inhibition of Hepatic Sulf2 in vivo Corrects Postprandial Dyslipidemia in Type 2 Diabetic Mice
    Hassing, Carlijne
    Mooij, Hans L.
    Guo, Shuling
    Monia, Brett
    Dallinga-Thie, Geesje M.
    Nieuwdorp, Max
    Chen, Keyang
    Stroes, Erik S.
    Williams, Kevin Jon
    CIRCULATION, 2011, 124 (21)
12345