Efficacy and safety of esaxerenone (CS-3150) in Japanese patients with type 2 diabetes and macroalbuminuria: a multicenter, single-arm, open-label phase III study

被引：0
|
作者：
Sadayoshi Ito
Naoki Kashihara
Kenichi Shikata
Masaomi Nangaku
Takashi Wada
Yasuyuki Okuda
Tomoko Sawanobori
机构：
[1] Tohoku University School of Medicine,Division of Nephrology, Endocrinology and Vascular Medicine, Department of Medicine
[2] Katta General Hospital,Center for Innovative Clinical Medicine
[3] Department of Nephrology and Hypertension,Division of Nephrology and Endocrinology, Graduate School of Medicine
[4] Kawasaki Medical School,Department of Nephrology and Laboratory Medicine
[5] Okayama University Hospital,Data Intelligence Department
[6] The University of Tokyo,Clinical Development Department
[7] Kanazawa University,undefined
[8] Daiichi Sankyo Co.,undefined
[9] Ltd.,undefined
[10] Daiichi Sankyo Co.,undefined
[11] Ltd.,undefined
来源：
Clinical and Experimental Nephrology | 2021年 / 25卷
关键词：
Esaxerenone; Macroalbuminuria; Phase III; Type 2 diabetes; Urinary albumin-to-creatinine ratio;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1070 / 1078
页数：8
相关论文
共 50 条
  • [1] Efficacy and safety of esaxerenone (CS-3150) in Japanese patients with type 2 diabetes and macroalbuminuria: a multicenter, single-arm, open-label phase III study
    Ito, Sadayoshi
    Kashihara, Naoki
    Shikata, Kenichi
    Nangaku, Masaomi
    Wada, Takashi
    Okuda, Yasuyuki
    Sawanobori, Tomoko
    CLINICAL AND EXPERIMENTAL NEPHROLOGY, 2021, 25 (10) : 1070 - 1078
  • [2] A Multicenter, Open-Label, Single-Arm, Phase 2 Study to Evaluate the Efficacy and Safety of Hetrombopag in Patients with Severe Aplastic Anemia (SAA)
    Zhang, Fengkui
    Peng, Guangxin
    He, Guangsheng
    Chang, Hong
    Gao, Sujun
    Liu, Xinjian
    Chen, Tong
    Li, Pei
    Han, Bing
    Miao, Miao
    Ge, Zheng
    Ge, Xiaoyan
    Li, Fei
    Li, Yingmei
    Wang, Shunqing
    Wang, Yi
    Shen, Yaqi
    Tai, Yanfei
    Zhang, Tao
    Zhu, Bo
    Zou, Jianjun
    BLOOD, 2020, 136
  • [3] Efficacy and safety of ropeginterferon alfa-2b in Japanese patients with polycythemia vera: an open-label, single-arm, phase 2 study
    Yoko Edahiro
    Kohshi Ohishi
    Akihiko Gotoh
    Katsuto Takenaka
    Hirohiko Shibayama
    Takayuki Shimizu
    Kensuke Usuki
    Kazuya Shimoda
    Masafumi Ito
    Scott A. VanWart
    Oleh Zagrijtschuk
    Albert Qin
    Hiroaki Kawase
    Narihisa Miyachi
    Toshiaki Sato
    Norio Komatsu
    Keita Kirito
    International Journal of Hematology, 2022, 116 : 215 - 227
  • [4] Efficacy and safety of ropeginterferon alfa-2b in Japanese patients with polycythemia vera: an open-label, single-arm, phase 2 study
    Edahiro, Yoko
    Ohishi, Kohshi
    Gotoh, Akihiko
    Takenaka, Katsuto
    Shibayama, Hirohiko
    Shimizu, Takayuki
    Usuki, Kensuke
    Shimoda, Kazuya
    Ito, Masafumi
    VanWart, Scott A.
    Zagrijtschuk, Oleh
    Qin, Albert
    Kawase, Hiroaki
    Miyachi, Narihisa
    Sato, Toshiaki
    Komatsu, Norio
    Kirito, Keita
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2022, 116 (02) : 215 - 227
  • [5] Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
    Hiroshi Itoh
    Sadayoshi Ito
    Hiromi Rakugi
    Yasuyuki Okuda
    Satoshi Nishioka
    Hypertension Research, 2019, 42 : 1572 - 1581
  • [6] Efficacy and safety of dosage-escalation of low-dosage esaxerenone added to a RAS inhibitor in hypertensive patients with type 2 diabetes and albuminuria: a single-arm, open-label study
    Itoh, Hiroshi
    Ito, Sadayoshi
    Rakugi, Hiromi
    Okuda, Yasuyuki
    Nishioka, Satoshi
    HYPERTENSION RESEARCH, 2019, 42 (10) : 1572 - 1581
  • [7] A Multicenter, Open-Label, Single-Arm Study to Evaluate the Efficacy and Safety of Saroglitazar in Patients With Primary Biliary Cholangitis
    Vuppalanchi, Raj
    Gonzalez-Huezo, Ma Sarai
    Payan-Olivas, Ramon
    Munoz-Espinosa, Linda E.
    Shaikh, Farheen
    Cruz-Lopez, Jose L. Pio
    Parmar, Deven
    CLINICAL AND TRANSLATIONAL GASTROENTEROLOGY, 2021, 12 (04) : E00327
  • [8] Efficacy and safety of tunlametinib in patients with advanced NRAS-mutant melanoma: A multicenter, open-label, single-arm, phase 2 study.
    Si, Lu
    Zou, Zhengyun
    Zhang, Weizhen
    Fang, Meiyu
    Zhang, Xiaoshi
    Luo, Zhiguo
    Chen, Jing
    Huang, Gang
    Zhang, Peng
    Cheng, Ying
    Liu, Jiwei
    Liu, Jiyan
    Zhang, Junping
    Wu, Di
    Chen, Yu
    Ma, Xiaobiao
    Wei, Xiaoting
    Sun, Peng
    Jia, Zhongwei
    Guo, Jun
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [9] Clinical Efficacy and Safety of Nivolumab: Results of a Multicenter, Open-label, Single-arm, Japanese Phase II study in Malignant Pleural Mesothelioma (MERIT)
    Okada, Morihito
    Kijima, Takashi
    Aoe, Keisuke
    Kato, Terufumi
    Fujimoto, Nobukazu
    Nakagawa, Kazuhiko
    Takeda, Yuichiro
    Hida, Toyoaki
    Kanai, Kuninobu
    Imamura, Fumio
    Oizumi, Satoshi
    Takahashi, Toshiaki
    Takenoyama, Mitsuhiro
    Tanaka, Hiroshi
    Hirano, Jun
    Namba, Yoshinobu
    Ohe, Yuichiro
    CLINICAL CANCER RESEARCH, 2019, 25 (18) : 5485 - 5492
  • [10] Correction to: Efficacy and safety of ropeginterferon alfa-2b in Japanese patients with polycythemia vera: an open-label, single-arm, phase 2 study
    Yoko Edahiro
    Kohshi Ohishi
    Akihiko Gotoh
    Katsuto Takenaka
    Hirohiko Shibayama
    Takayuki Shimizu
    Kensuke Usuki
    Kazuya Shimoda
    Masafumi Ito
    Scott A. VanWart
    Oleh Zagrijtschuk
    Albert Qin
    Hiroaki Kawase
    Narihisa Miyachi
    Toshiaki Sato
    Norio Komatsu
    Keita Kirito
    International Journal of Hematology, 2022, 116 : 642 - 643
12345