Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine

被引:0
|
作者
Stefania Bulotta
Marilena Celano
Giuseppe Costante
Diego Russo
机构
[1] University “Magna Graecia” of Catanzaro,Department of Health Sciences
[2] Institut Jules Bordet Comprehensive Cancer Center,Endocrinology Clinic, Internal Medicine Department
来源
Endocrine | 2016年 / 52卷
关键词
Differentiated thyroid cancer; Radioiodine; Molecular targets; Re-differentiation strategies; Nanodevices;
D O I
暂无
中图分类号
学科分类号
摘要
Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent identification of genetic and epigenetic alterations present in almost all differentiated tumors has revealed novel molecular targets, which can hopefully be exploited to create new treatments for these tumors. This review looks briefly at some of the innovative strategies currently being investigated for the treatment the radioiodine-resistant thyroid cancers.
引用
收藏
页码:214 / 221
页数:7
相关论文
共 50 条
  • [31] Lenvatinib - A multikinase inhibitor for radioiodine-refractory differentiated thyroid cancer
    Hewett, Yvonne
    Ghimire, Subash
    Farooqi, Bilal
    Shah, Binay K.
    JOURNAL OF ONCOLOGY PHARMACY PRACTICE, 2018, 24 (01) : 28 - 32
  • [32] Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective
    Fabian Pitoia
    Rafael Selbach Scheffel
    Ines Califano
    Alicia Gauna
    Hernán Tala
    Fernanda Vaisman
    Alejandro Roman Gonzalez
    Ana Oliveira Hoff
    Ana Luiza Maia
    Reviews in Endocrine and Metabolic Disorders, 2024, 25 : 109 - 121
  • [33] Impact of age on survival in radioiodine refractory differentiated thyroid cancer patients
    Saie, C.
    Wassermann, J.
    Mathy, E.
    Chereau, N.
    Leenhardt, L.
    du Montcel, S. Tezenas
    Buffet, C.
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2021, 184 (05) : 667 - 676
  • [34] Management of radioiodine refractory differentiated thyroid cancer: the Latin American perspective
    Pitoia, Fabian
    Scheffel, Rafael Selbach
    Califano, Ines
    Gauna, Alicia
    Tala, Hernan
    Vaisman, Fernanda
    Gonzalez, Alejandro Roman
    Hoff, Ana Oliveira
    Maia, Ana Luiza
    REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2024, 25 (01): : 109 - 121
  • [35] Efficacy of pazopanib in progressive, radioiodine-refractory, metastatic differentiated thyroid cancers: results of a phase 2 consortium study
    Bible, Keith C.
    Suman, Vera J.
    Molina, Julian R.
    Smallridge, Robert C.
    Maples, William J.
    Menefee, Michael E.
    Rubin, Joseph
    Sideras, Kostandinos
    Morris, John C., III
    McIver, Bryan
    Burton, Jill K.
    Webster, Kevin P.
    Bieber, Carolyn
    Traynor, Anne M.
    Flynn, Patrick J.
    Goh, Boon Cher
    Tang, Hui
    Ivy, Susan Percy
    Erlichman, Charles
    LANCET ONCOLOGY, 2010, 11 (10): : 962 - 972
  • [37] Reduction of Salivary Gland Damage During Radioiodine Therapy for Differentiated Thyroid Cancers
    Byeong-Cheol Ahn
    Nuclear Medicine and Molecular Imaging, 2020, 54 : 126 - 127
  • [38] THYROTROPIN RECEPTORS, TUMOR RADIOIODINE CONCENTRATION AND THYROGLOBULIN SECRETION IN DIFFERENTIATED THYROID CANCERS
    EDMONDS, CJ
    KERMODE, JC
    BRITISH JOURNAL OF CANCER, 1985, 52 (04) : 537 - 541
  • [39] Radioiodine in differentiated thyroid cancer
    Borner, AR
    MullerGartner, HW
    ZENTRALBLATT FUR CHIRURGIE, 1997, 122 (04): : 274 - 285
  • [40] Radioiodine refractoriness score: A multivariable prediction model for postoperative radioiodine-refractory differentiated thyroid carcinomas
    Li, Genpeng
    Lei, Jianyong
    Song, Linlin
    Jiang, Ke
    Wei, Tao
    Li, Zhihui
    Gong, Rixiang
    Zhu, Jingqiang
    CANCER MEDICINE, 2018, 7 (11): : 5448 - 5456