Effect of semax on homeostasis of gastric mucosa in albino rats

被引：0
|
作者：
S. E. Zhuikova
E. A. Smirnova
Z. V. Bakaeva
G. E. Samonina
I. P. Ashmarin
机构：
[1] Biological Faculty of M. V. Lomonosov Moscow State University,Department of Human and Animal Physiology
来源：
Bulletin of Experimental Biology and Medicine | 2000年 / 130卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The ACTH4–7 analogue Semax administered intrapeitoneally in a dose of 50 μg/kg 1 h before exposure to ulcerogenic factors (ethanol, water immersion immobilization stress) protected gastric mucosa from damage. Postoperative treatment with Semax for 5 days after application of glacial acetic acid on the mucosa prevented acetic acid-induced ulcers and promoted their healing. The antiulcer effects of Semax in the studied dose were comparable with those of tripeptide Pro-Gly-Pro in a dose of 1 mg/kg.
引用
收藏
页码：871 / 873
页数：2
相关论文
共 50 条
  • [31] NO homeostasis in Helicobacter pylori-infected gastric mucosa
    Journal of Gastroenterology, 1999, 34 (6) : 717 - 720
  • [32] Selank and its metabolites maintain homeostasis in the gastric mucosa
    Pavlov, T. S.
    Samonina, G. E.
    Bakaeva, Z. V.
    Zolotarev, Yu. A.
    Guseva, A. A.
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2007, 143 (01) : 51 - 53
  • [33] Effect of semax and semax-heparin mixture on isolated heart activity after total ischemia in rats
    A. V. Orlov
    A. E. Khomutov
    I. V. Mukhina
    Yu. B. Zimin
    S. B. Parin
    D. V. Kozin
    Bulletin of Experimental Biology and Medicine, 1999, 128 : 1084 - 1086
  • [34] Selank and its metabolites maintain homeostasis in the gastric mucosa
    T. S. Pavlov
    G. E. Samonina
    Z. V. Bakaeva
    Yu. A. Zolotarev
    A. A. Guseva
    Bulletin of Experimental Biology and Medicine, 2007, 143 : 51 - 53
  • [35] EFFECT OF BILATERAL ADRENALECTOMY ON GASTRIC-MUCOSAL BARRIER IN ALBINO-RATS
    SOMASUNDARAM, K
    GANGULY, AK
    INDIAN JOURNAL OF MEDICAL RESEARCH, 1986, 84 : 657 - 663
  • [36] EFFECT OF INCLUSION OF EXTRANEOUS CELLULOSE ON GASTRIC EMPTYING TIME IN ADULT ALBINO RATS
    SHURPALEKAR, KS
    SUNDARAVALLI, OE
    RAO, MN
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1969, 47 (04) : 387 - +
  • [37] Effect of semax and semax-heparin mixture on isolated heart activity after total ischemia in rats
    Orlov, AV
    Khomutov, AE
    Mukhina, IV
    Zimin, YB
    Parin, SB
    Kozin, DV
    BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 1999, 128 (11) : 1084 - 1086
  • [38] GASTRIC SURGERY IN ALBINO RATS . RESEARCH ON METHODS
    MAURER, W
    ZEITSCHRIFT FUR GASTROENTEROLOGIE, 1967, 5 (03): : 183 - &
  • [39] EFFECT OF PREMATURE WEANING ON SENSITIVITY OF RATS TO EXPERIMENTAL EROSIONS OF GASTRIC MUCOSA
    ERDOSOVA, R
    FLANDERA, V
    KRECEK, J
    WIENER, P
    PHYSIOLOGIA BOHEMOSLOVACA, 1967, 16 (05): : 400 - &
  • [40] EFFECT OF SINGLE INTOXICATING DOSES OF ETHANOL ON GASTRIC AND INTESTINAL MUCOSA OF RATS
    GILLESPIE, R
    LUCAS, CC
    CANADIAN JOURNAL OF BIOCHEMISTRY AND PHYSIOLOGY, 1961, 39 (02): : 237 - &
12345