Effect of semax on homeostasis of gastric mucosa in albino rats

被引：0
|
作者：
S. E. Zhuikova
E. A. Smirnova
Z. V. Bakaeva
G. E. Samonina
I. P. Ashmarin
机构：
[1] Biological Faculty of M. V. Lomonosov Moscow State University,Department of Human and Animal Physiology
来源：
Bulletin of Experimental Biology and Medicine | 2000年 / 130卷
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摘要：
The ACTH4–7 analogue Semax administered intrapeitoneally in a dose of 50 μg/kg 1 h before exposure to ulcerogenic factors (ethanol, water immersion immobilization stress) protected gastric mucosa from damage. Postoperative treatment with Semax for 5 days after application of glacial acetic acid on the mucosa prevented acetic acid-induced ulcers and promoted their healing. The antiulcer effects of Semax in the studied dose were comparable with those of tripeptide Pro-Gly-Pro in a dose of 1 mg/kg.
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页码：871 / 873
页数：2
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