Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis

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作者
Jingjing Zhang
Yun Li
Hua Liu
Jiahui Zhang
Jie Wang
Jia Xia
Yu Zhang
Xiang Yu
Jinyan Ma
Masha Huang
Jiahui Wang
Liangzhe Wang
Qian Li
Rutao Cui
Wen Yang
Yingjie Xu
Weiwei Feng
机构
[1] Ruijin Hospital,Department of Obstetrics and Gynecology
[2] Shanghai Jiao Tong University School of Medicine,Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation
[3] Shanghai Jiao Tong University School of Medicine,Department of Nephrology, Renji Hospital, School of Medicine
[4] Shanghai Jiao Tong University,Department of Pathology
[5] Changzheng Hospital,Center for Brain Science, Shanghai Children’s Medical Center, Department of Anatomy and Physiology
[6] Second Military Medical University,Department of Dermatology
[7] Shanghai Jiao Tong University School of Medicine,undefined
[8] Shanghai Research Center for Brain Science and Brain-Inspired Intelligence,undefined
[9] Boston University School of Medicine,undefined
[10] State Key Laboratory of Oncogenes and Related Genes,undefined
关键词
PCMT1; Metastasis; Extracellular matrix; CRISPR/Cas9; Integrin-FAK-Src; Anoikis;
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