Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis

被引：0
|
作者：
Jingjing Zhang
Yun Li
Hua Liu
Jiahui Zhang
Jie Wang
Jia Xia
Yu Zhang
Xiang Yu
Jinyan Ma
Masha Huang
Jiahui Wang
Liangzhe Wang
Qian Li
Rutao Cui
Wen Yang
Yingjie Xu
Weiwei Feng
机构：
[1] Ruijin Hospital,Department of Obstetrics and Gynecology
[2] Shanghai Jiao Tong University School of Medicine,Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation
[3] Shanghai Jiao Tong University School of Medicine,Department of Nephrology, Renji Hospital, School of Medicine
[4] Shanghai Jiao Tong University,Department of Pathology
[5] Changzheng Hospital,Center for Brain Science, Shanghai Children’s Medical Center, Department of Anatomy and Physiology
[6] Second Military Medical University,Department of Dermatology
[7] Shanghai Jiao Tong University School of Medicine,undefined
[8] Shanghai Research Center for Brain Science and Brain-Inspired Intelligence,undefined
[9] Boston University School of Medicine,undefined
[10] State Key Laboratory of Oncogenes and Related Genes,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 41卷
关键词：
PCMT1; Metastasis; Extracellular matrix; CRISPR/Cas9; Integrin-FAK-Src; Anoikis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Genome-wide CRISPR/Cas9 library screen identifies PCMT1 as a critical driver of ovarian cancer metastasis
    Zhang, Jingjing
    Li, Yun
    Liu, Hua
    Zhang, Jiahui
    Wang, Jie
    Xia, Jia
    Zhang, Yu
    Yu, Xiang
    Ma, Jinyan
    Huang, Masha
    Wang, Jiahui
    Wang, Liangzhe
    Li, Qian
    Cui, Rutao
    Yang, Wen
    Xu, Yingjie
    Feng, Weiwei
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2022, 41 (01)
  • [2] A genome-wide CRISPR/Cas9 screen identifies octreotate radionuclide therapy
    Waldeck, Kelly
    Van Zuylekom, Jessica
    Cullinane, Carleen
    Gulati, Twishi
    Simpson, Kaylene J.
    Tothill, Richard W.
    Blyth, Benjamin
    Hicks, Rodney J.
    THERANOSTICS, 2023, 13 (14): : 4745 - 4761
  • [3] Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
    Lai Wei
    Derek Lee
    Cheuk-Ting Law
    Misty Shuo Zhang
    Jialing Shen
    Don Wai-Ching Chin
    Allen Zhang
    Felice Ho-Ching Tsang
    Ceci Lok-Sze Wong
    Irene Oi-Lin Ng
    Carmen Chak-Lui Wong
    Chun-Ming Wong
    Nature Communications, 10
  • [4] Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC
    Wei, Lai
    Lee, Derek
    Law, Cheuk-Ting
    Zhang, Misty Shuo
    Shen, Jialing
    Chin, Don Wai-Ching
    Zhang, Allen
    Tsang, Felice Ho-Ching
    Wong, Ceci Lok-Sze
    Ng, Irene Oi-Lin
    Wong, Carmen Chak-Lui
    Wong, Chun-Ming
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [5] Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
    Wen, Wen
    Liao, Long
    Dai, Wei
    Zheng, Can-Can
    Tan, Xiang-Peng
    He, Yan
    Zhang, Qi-Hua
    Huang, Zhi-Hao
    Chen, Wen-You
    Qin, Yan-Ru
    Chen, Kui-Sheng
    He, Ming-Liang
    Law, Simon
    Lung, Maria Li
    He, Qing-Yu
    Li, Bin
    EBIOMEDICINE, 2023, 92
  • [6] CRISPR/Cas9 genome-wide gRNA library for target identification
    Tedesco, Donato
    Diehl, Paul
    Makhanov, Mikhail
    Baron, Sylvain
    Suchkov, Dmitry
    Frangou, Costa
    Chenchik, Alex
    CANCER RESEARCH, 2016, 76
  • [7] CRISPR/Cas9 genome-wide gRNA library for target identification
    Diehl, P.
    Tedesco, D.
    Makhanov, M.
    Baron, S.
    Suchkov, D.
    Frangou, C.
    Chenchik, A.
    EUROPEAN JOURNAL OF CANCER, 2016, 69 : S44 - S44
  • [8] GENOME-WIDE CRISPR/CAS9 LIBRARY SCREENING IDENTIFIED PAK1 AS A CRITICAL DRIVER FOR LENVATINIB RESISTANCE IN HCC.
    Huang, Shanzhou
    Zhang, Chuanzhao
    Hou, Baohua
    Wu, Linwei
    TRANSPLANTATION, 2020, 104 (09) : S42 - S42
  • [9] Genome-wide CRISPR/Cas9 library screening to identify PAK1 as a critical driver for lenvatinib resistance in HCC.
    Huang, Shanzhou
    zhang, chuanzhao
    Hou, Baohua
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [10] A genome-wide CRISPR/Cas9 screen identifies calreticulin as a selective repressor of ATF6α
    Tung, Joanne
    Huang, Lei
    George, Ginto
    Harding, Heather P.
    Ron, David
    Ordonez, Adriana
    ELIFE, 2024, 13
12345