Liposomes with Incorporated MHC Class Il/Peptide Complexes as Antigen Presenting Vesicles for Specific T Cell Activation

被引：0
|
作者：
Annemiek J. M. L. van Rensen
Marca H. M. Wauben
Mayken C. Grosfeld-Stulemeyer
Willem van Eden
Daan J. A. Crommelin
机构：
[1] Utrecht University,Department of Pharmaceutics, Faculty of Pharmacy, Utrecht Institute for Pharmaceutical Sciences (UIPS)
[2] Utrecht University,Institute of Infectious Diseases and Immunology, Department of Immunology, Faculty of Veterinary Medicine
来源：
Pharmaceutical Research | 1999年 / 16卷
关键词：
liposomes; MHC class II; peptides; FACS analysis; T lymphocytes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. The purpose of this study was to design a well-characterized liposomal carrier system for multivalent antigen presentation in order to activate T cells.
引用
收藏
页码：198 / 204
页数：6
相关论文
共 50 条
  • [21] KINETICS AND AFFINITY OF REACTIONS BETWEEN AN ANTIGEN-SPECIFIC T-CELL RECEPTOR AND PEPTIDE-MHC COMPLEXES
    SYKULEV, Y
    BRUNMARK, A
    JACKSON, M
    COHEN, RJ
    PETERSON, PA
    EISEN, HN
    IMMUNITY, 1994, 1 (01) : 15 - 22
  • [22] CD4+ T cells cross-compete for MHC class II-restricted peptide antigen complexes on the surface of antigen presenting cells
    Hayball, JD
    Robinson, BWS
    Lake, RA
    IMMUNOLOGY AND CELL BIOLOGY, 2004, 82 (02): : 103 - 111
  • [23] Enrichment of antigen-specific T lymphocytes by panning on immobilized MHC-peptide complexes
    Bousso, P
    Michel, F
    Pardigon, N
    Bercovici, N
    Liblau, R
    Kourilsky, P
    Abastado, JP
    IMMUNOLOGY LETTERS, 1997, 59 (02) : 85 - 91
  • [24] Soluble MHC II peptide complexes induce antigen-specific apoptosis in T cells
    Nag, B
    Kendrick, T
    Arimilli, S
    Yu, SCT
    Sriram, S
    CELLULAR IMMUNOLOGY, 1996, 170 (01) : 25 - 33
  • [25] Soluble divalent class I mhc fusion proteins induce in vivo antigen-specific T cell activation
    DeLay, M
    Hirsch, R
    FASEB JOURNAL, 1999, 13 (04): : A625 - A625
  • [26] DIFFERENTIAL REQUIREMENTS FOR CLASS II MHC ANTIGEN IN HUMAN T-CELL ACTIVATION
    GOEKEN, NE
    ECKERLE, MK
    LIOUBIN, PJ
    STAGGS, TS
    TRANSPLANTATION, 1984, 38 (06) : 714 - 719
  • [27] Collective dynamics of class I MHC/peptide complexes and binding to T cell receptors
    Haliloglu, T
    Bahar, I
    Jernigan, RL
    BIOPHYSICAL JOURNAL, 2000, 78 (01) : 34A - 34A
  • [28] ANTIGEN-PRESENTING CELL-T CELL-INTERACTION IN THE CHICKEN IS MHC CLASS-II ANTIGEN RESTRICTED
    VAINIO, O
    VEROMAA, T
    EEROLA, E
    TOIVANEN, P
    RATCLIFFE, MJH
    JOURNAL OF IMMUNOLOGY, 1988, 140 (09): : 2864 - 2868
  • [29] Peptide-MHC class II dimers as therapeutics to modulate antigen-specific T cell responses in autoimmune diabetes
    Masteller, EL
    Warner, MR
    Ferlin, W
    Judkowski, V
    Wilson, D
    Glaichenhaus, N
    Bluestone, JA
    JOURNAL OF IMMUNOLOGY, 2003, 171 (10): : 5587 - 5595
  • [30] Biodegradable Nanoellipsoidal Artificial Antigen Presenting Cells for Antigen Specific T-Cell Activation
    Meyer, Randall A.
    Sunshine, Joel C.
    Perica, Karlo
    Kosmides, Alyssa K.
    Aje, Kent
    Schneck, Jonathan P.
    Green, Jordan J.
    SMALL, 2015, 11 (13) : 1519 - 1525
12345