Translational stem cell therapy for amyotrophic lateral sclerosis

被引:0
|
作者
Nicholas M. Boulis
Thais Federici
Jonathan D. Glass
J. Simon Lunn
Stacey A. Sakowski
Eva L. Feldman
机构
[1] Emory University,Department of Neurosurgery
[2] Emory University,Department of Neurology
[3] University of Michigan,Department of Neurology
来源
Nature Reviews Neurology | 2012年 / 8卷
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摘要
The first-in-human phase I trial of stem cell transplantation for amyotrophic lateral sclerosis was approved by the FDA in 2009 and is ongoing. In their Perspectives article, Eva Feldman and colleagues, who are conducting the trial, discuss the preclinical research supporting this therapeutic approach, key aspects of the trial design to overcome translational issues, and ongoing challenges to address in future studies.
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页码:172 / 176
页数:4
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