共 50 条
- [21] Compendium of aberrant DNA methylation and histone modifications in cancer[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2014, 455 (1-2) : 3 - 9Hattori, Naoko论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Div Epigenom, Chuo Ku, Tokyo 1040045, Japan Natl Canc Ctr, Div Epigenom, Chuo Ku, Tokyo 1040045, JapanUshijima, Toshikazu论文数: 0 引用数: 0 h-index: 0机构: Natl Canc Ctr, Div Epigenom, Chuo Ku, Tokyo 1040045, Japan Natl Canc Ctr, Div Epigenom, Chuo Ku, Tokyo 1040045, Japan
- [22] Initiation of aberrant DNA methylation patterns and heterogeneity in precancerous lesions of human hepatocellular cancer[J]. EPIGENETICS, 2017, 12 (03) : 215 - 225Hlady, Ryan A.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USAZhou, Dan论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USAPuszyk, William论文数: 0 引用数: 0 h-index: 0机构: Univ Florida, Shands Canc Ctr, Gainesville, FL USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USARoberts, Lewis R.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USALiu, Chen论文数: 0 引用数: 0 h-index: 0机构: Rutgers State Univ, Dept Pathol & Lab Med, Newark, NJ USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USARobertson, Keith D.论文数: 0 引用数: 0 h-index: 0机构: Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USA Mayo Clin, Ctr Individualized Med, Rochester, MN USA Mayo Clin, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USA
- [23] Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer[J]. Genome Biology, 17Holger Heyn论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyEnrique Vidal论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyHumberto J. Ferreira论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyMiguel Vizoso论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologySergi Sayols论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyAntonio Gomez论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologySebastian Moran论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyRaquel Boque-Sastre论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologySonia Guil论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyAnna Martinez-Cardus论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyCharles Y. Lin论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyRomina Royo论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyJose V. Sanchez-Mut论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyRamon Martinez论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyMarta Gut论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyDavid Torrents论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyModesto Orozco论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyIvo Gut论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyRichard A. Young论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical OncologyManel Esteller论文数: 0 引用数: 0 h-index: 0机构: Cancer Epigenetics and Biology Program (PEBC),Department of Medical Oncology
- [24] miRNA Gene Promoters Are Frequent Targets of Aberrant DNA Methylation in Human Breast Cancer[J]. PLOS ONE, 2013, 8 (01):Vrba, Lukas论文数: 0 引用数: 0 h-index: 0机构: Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USA Acad Sci Czech Republic, Inst Plant Mol Biol, Ctr Biol, Vvi, CR-37005 Ceske Budejovice, Czech Republic Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USAMunoz-Rodriguez, Jose L.论文数: 0 引用数: 0 h-index: 0机构: Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USA Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USAStampfer, Martha R.论文数: 0 引用数: 0 h-index: 0机构: Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USA Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Div Life Sci, Berkeley, CA 94720 USA Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USAFutscher, Bernard W.论文数: 0 引用数: 0 h-index: 0机构: Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USA Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA Univ Arizona, Arizona Canc Ctr, Tucson, AZ 85721 USA
- [25] Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer[J]. GENOME BIOLOGY, 2016, 17Heyn, Holger论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainVidal, Enrique论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainFerreira, Humberto J.论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainVizoso, Miguel论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainSayols, Sergi论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainGomez, Antonio论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainMoran, Sebastian论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainBoque-Sastre, Raquel论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainGuil, Sonia论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainMartinez-Cardus, Anna论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainLin, Charles Y.论文数: 0 引用数: 0 h-index: 0机构: Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA MIT, Computat & Syst Biol Program, Cambridge, MA 02139 USA Dana Farber Canc Inst, Dept Med Oncol, 44 Binney St, Boston, MA 02115 USA Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainRoyo, Romina论文数: 0 引用数: 0 h-index: 0机构: Joint Biomed Res Inst Barcelona Supercomp Ctr IRB, Program Computat Biol, Baldiri Reixac 10-12, Barcelona 08028, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainSanchez-Mut, Jose V.论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainMartinez, Ramon论文数: 0 引用数: 0 h-index: 0机构: Univ Gottingen, Dept Neurosurg, Robert Koch Str 40, D-37075 Gottingen, Germany Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainGut, Marta论文数: 0 引用数: 0 h-index: 0机构: Ctr Nacl Anal Genom, Barcelona, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainTorrents, David论文数: 0 引用数: 0 h-index: 0机构: Joint Biomed Res Inst Barcelona Supercomp Ctr IRB, Program Computat Biol, Baldiri Reixac 10-12, Barcelona 08028, Catalonia, Spain ICREA, Barcelona 08010, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainOrozco, Modesto论文数: 0 引用数: 0 h-index: 0机构: Joint Biomed Res Inst Barcelona Supercomp Ctr IRB, Program Computat Biol, Baldiri Reixac 10-12, Barcelona 08028, Catalonia, Spain Inst Res Biomed IRB Barcelona, Baldiri Reixac 10-12, Barcelona 08028, Catalonia, Spain Univ Barcelona, Dept Biochem & Mol Biol, E-08028 Barcelona, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainGut, Ivo论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainYoung, Richard A.论文数: 0 引用数: 0 h-index: 0机构: Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA 02142 USA MIT, Dept Biol, Cambridge, MA 02139 USA Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, SpainEsteller, Manel论文数: 0 引用数: 0 h-index: 0机构: Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain ICREA, Barcelona 08010, Catalonia, Spain Univ Barcelona, Dept Physiol Sci 2, Sch Med, E-08036 Barcelona, Catalonia, Spain Bellvitge Biomed Res Inst IDIBELL, Canc Epigenet & Biol Program PEBC, Barcelona 08908, Catalonia, Spain
- [26] ABERRANT DNA METHYLATION IN BENIGN AND MALIGNANT HUMAN THYROID NEOPLASMS[J]. CLINICAL RESEARCH, 1991, 39 (01): : A25 - A25MATSUO, K论文数: 0 引用数: 0 h-index: 0机构: UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048 UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048TANG, SH论文数: 0 引用数: 0 h-index: 0机构: UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048 UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048FAGIN, JA论文数: 0 引用数: 0 h-index: 0机构: UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048 UNIV CALIF LOS ANGELES,CEDARS SINAI MED CTR,SCH MED,DEPT MED,LOS ANGELES,CA 90048
- [27] Aberrant DNA Methylation in Keratoacanthoma[J]. PLoS One, 2016, 11 (10):Nobeyama, Yoshimasa论文数: 0 引用数: 0 h-index: 0机构: Jikei Univ, Dept Dermatol, Sch Med, Tokyo, Japan Jikei Univ, Dept Dermatol, Sch Med, Tokyo, JapanNakagawa, Hidemi论文数: 0 引用数: 0 h-index: 0机构: Jikei Univ, Dept Dermatol, Sch Med, Tokyo, Japan Jikei Univ, Dept Dermatol, Sch Med, Tokyo, Japan
- [28] DNA Methylation Aberrant in Atherosclerosis[J]. FRONTIERS IN PHARMACOLOGY, 2022, 13Dai, Yao论文数: 0 引用数: 0 h-index: 0机构: Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R China Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R ChinaChen, Danian论文数: 0 引用数: 0 h-index: 0机构: Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R China Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R ChinaXu, Tingting论文数: 0 引用数: 0 h-index: 0机构: Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R China Anhui Med Univ, Affiliated Hosp 1, Dept Cardiol, Hefei, Peoples R China
- [29] Aberrant Methylation of HLTF Gene in Human Esophageal Cancer[J]. INTERNATIONAL JOURNAL OF HUMAN GENETICS, 2016, 16 (1-2) : 70 - 76Wang, Liang论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Shenzhen Key Lab Translat Med Tumor, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaZhang, Xiaojing论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaYin, Peng论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaGao, Yan论文数: 0 引用数: 0 h-index: 0机构: Guangdong Med Coll, Nanshan Hosp, Shenzhen 518052, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaZhang, Yuan论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaFeng, Xianling论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaChen, Si论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaYu, Huimin论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaHuang, Weiling论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaHuang, Yong论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaJian, Qianhe论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaZhao, Zhenfu论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaFan, Xinmin论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R ChinaJin, Zhe论文数: 0 引用数: 0 h-index: 0机构: Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Shenzhen Key Lab Micromol Innovatal Drugs, Shenzhen 518060, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Shenzhen Key Lab Translat Med Tumor, Shenzhen 518060, Guangdong, Peoples R China Peking Univ, Shenzhen Grad Sch, Sch Chem Biol & Biotechnol, Lab Chem Genom, Shenzhen 518055, Guangdong, Peoples R China Shenzhen Univ, Sch Med, Dept Pathol, Rm 703,3688 Nanhai Ave, Shenzhen 518060, Guangdong, Peoples R China
- [30] Accumulation of aberrant DNA methylation during colorectal cancer development[J]. WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (04) : 978 - 987论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Kaneda, Atsushi论文数: 0 引用数: 0 h-index: 0机构: Univ Tokyo, Res Ctr Adv Sci & Technol, Genome Sci Div, Tokyo 1138654, Japan Chiba Univ, Grad Sch Med, Dept Mol Oncol, Chiba 2608670, Japan Japan Sci & Technol Agcy, CREST, Kawaguchi, Saitama 3320012, Japan Yokohama City Univ, Sch Med, Dept Gastroenterol, Yokohama, Kanagawa 2360027, Japan