L-type Ca2+ channels activation and contraction elicited by myricetin on vascular smooth muscles

被引:0
|
作者
Fabio Fusi
Simona Saponara
Maria Frosini
Beatrice Gorelli
Giampietro Sgaragli
机构
[1] Università degli Studi di Siena,Dipartimento di Scienze Anatomiche e Biomediche
关键词
(S)-(-)-Bay K 8644; Myricetin; Vascular smooth muscle; Whole-cell patch-clamp; Wine polyphenols;
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学科分类号
摘要
The effects of myricetin (3,3’,4’,5,5’,7-hesahydroxyflavone), a natural flavonoid found in edible plants, were studied on vascular smooth muscle L-type Ca2+ channels by comparing its mechanical, radioligand binding, and electrophysiological properties to those of the Ca2+ channel agonist (S)-(-)-Bay K 8644.
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页码:470 / 478
页数:8
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