Perampanel—new promise for refractory epilepsy?

被引：0
|
作者：
Wolfgang Löscher
Dieter Schmidt
机构：
[1] Toxicology and Pharmacy,Department of Pharmacology
[2] University of Veterinary Medicine,undefined
[3] Epilepsy Research Group,undefined
来源：
Nature Reviews Neurology | 2012年 / 8卷
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摘要：
Three recent phase III trials have shown that adjunctive treatment with perampanel—a first-in-class, noncompetitive AMPA antagonist—decreases seizure frequency in patients with refractory focal epilepsy. Although the introduction of perampanel offers more treatment choice for epilepsy, whether it brings urgently needed clinical benefit over existing drugs remains to be addressed.
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页码：661 / 662
页数：1
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