Discovery of potent β-secretase (bace-1) inhibitors by the synthesis of isophthalamide-containing hybrids

被引：0
|
作者：
Yi-ping Zhu
Kun Xiao
Hai-ping Yu
Lan-ping Ma
Bing Xiong
Hai-yan Zhang
Xin Wang
Jing-ya Li
Jia Li
Jing-kang Shen
机构：
[1] The State Key Laboratory of Drug Research,
[2] Shanghai Institute of Materia Medica,undefined
[3] Chinese Academy of Sciences,undefined
[4] The National Center for Drug Screening,undefined
来源：
Acta Pharmacologica Sinica | 2009年 / 30卷
关键词：
aspartyl protease β-secretase; hydroxyethylene; solid phase; biological evaluation; molecular modeling;
D O I：
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学科分类号：
摘要：
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页码：259 / 269
页数：10
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