The emerging roles of N6-methyladenosine (m6A)-modified long non-coding RNAs in human cancers

被引：0
|
作者：
Jingwen Liu
Wei Zhao
Leyu Zhang
Xi Wang
机构：
[1] Tianjin Medical University,The School and Hospital of Stomatology
来源：
Cell Death Discovery | / 8卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
N6-methyladenosine (m6A) epitranscriptional modifications widely exist in RNA, which play critical roles in RNA metabolism and biogenesis processes. Long non-coding RNAs (lncRNAs) are class of non-coding RNAs longer than 200 nucleotides without protein-coding ability. LncRNAs participate in a large number of vital biological progressions. With the great improvement of molecular biology, m6A and lncRNAs are attracting more attention from researchers and scholars. In this review, we overview the current status of m6A and lncRNAs based on the latest research, and propose some viewpoints for future research perspectives.
引用
收藏
相关论文
共 50 条
  • [21] Potential roles of N6-methyladenosine (m6A) in immune cells
    Chang Liu
    Zhe Yang
    Rong Li
    Yanju Wu
    Ming Chi
    Shuting Gao
    Xun Sun
    Xin Meng
    Biao Wang
    Journal of Translational Medicine, 19
  • [22] Potential roles of N6-methyladenosine (m6A) in immune cells
    Liu, Chang
    Yang, Zhe
    Li, Rong
    Wu, Yanju
    Chi, Ming
    Gao, Shuting
    Sun, Xun
    Meng, Xin
    Wang, Biao
    JOURNAL OF TRANSLATIONAL MEDICINE, 2021, 19 (01)
  • [23] N6-methyladenosine (m6A) RNA modification in gastrointestinal tract cancers: roles, mechanisms, and applications
    Hu, Bin-bin
    Wang, Xiao-yan
    Gu, Xu-Yu
    Zou, Chen
    Gao, Zhen-jun
    Zhang, Heng
    Fan, Yu
    MOLECULAR CANCER, 2019, 18 (01)
  • [24] N6-methyladenosine (m6A) RNA modification in gastrointestinal tract cancers: roles, mechanisms, and applications
    Bin-bin Hu
    Xiao-yan Wang
    Xu-Yu Gu
    Chen Zou
    Zhen-jun Gao
    Heng Zhang
    Yu Fan
    Molecular Cancer, 18
  • [25] The Impacts of Non-coding RNAs and N6-Methyladenosine on Cancer: Past, Present and Future
    Xu, Zhaoyuan
    Ji, Guohua
    Cui, Ying
    Cui, Xiaobo
    CURRENT CANCER DRUG TARGETS, 2021, 21 (05) : 375 - 385
  • [26] Novel Insights into The Roles of N6-methyladenosine (m6A) Modification and Autophagy in Human Diseases
    Liang, Jiaxin
    Sun, Jingwen
    Zhang, Wei
    Wang, Xiwen
    Xu, Ying
    Peng, Yuan
    Zhang, Ling
    Xiong, Wenqian
    Liu, Yi
    Liu, Hengwei
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2023, 19 (02): : 705 - 720
  • [27] Regulation of m6A (N6-Methyladenosine) methylation modifiers in solid cancers
    Singh, Sakshi
    Gupta, Sudha
    Abhishek, Rajul
    Sachan, Manisha
    FUNCTIONAL & INTEGRATIVE GENOMICS, 2024, 24 (06)
  • [28] Critical Roles of N6-Methyladenosine (m6A) in Cancer and Virus Infection
    Asada, Ken
    Bolatkan, Amina
    Takasawa, Ken
    Komatsu, Masaaki
    Kaneko, Syuzo
    Hamamoto, Ryuji
    BIOMOLECULES, 2020, 10 (07) : 1 - 22
  • [29] N6-methyladenosine (m6A) modification of ribosomal RNAs (rRNAs): Critical roles in mRNA translation and diseases
    Lei, Kexin
    Lin, Shuibin
    Yuan, Quan
    GENES & DISEASES, 2023, 10 (01) : 126 - 134
  • [30] N6-methyladenosine (m6A) RNA modification in human cancer
    Huo, Fu-Chun
    Zhu, Zhi-Man
    Pei, Dong-Sheng
    CELL PROLIFERATION, 2020, 53 (11)
12345